Gene map of the cow: conservation of linkage with mouse and man. Academic Article

abstract

• Cattle-hamster hybrid somatic cells segregating cattle chromosomes have been analyzed by cellulose-acetate electrophoresis for 28 enzyme gene products including the previously unassigned loci for GAPD, ITPA, ADA, ACO1, GDH, GUK, CAT, and GLO1. These 28 loci are organized into 21 independent syntenic groups bringing the composite bovine gene map to 35 loci on 24 syntenic groups. Thirty-two homologous genes now have been mapped in humans, mice, and cattle. Conservation of cattle and human linkage groups is evidenced by only three linkage discordancies among these 32 loci as contrasted to nine discordancies among the same loci in the human and mouse maps.

authors

• Womack, James

published proceedings

• J Hered

altmetric score

• 3

author list (cited authors)

• Womack, J. E., & Moll, Y. D.

citation count

• 204

complete list of authors

• Womack, JE||Moll, YD

publication date

• January 1986

publisher

• Oxford University Press (OUP)  Publisher

published in

• JOURNAL OF HEREDITY  Journal

keywords

• Animals
• Biological Evolution
• Cattle
• Chromosome Mapping
• Cricetinae
• Cricetulus
• ENZYMES
• Genes
• Genetic Linkage
• Haplorhini
• Humans
• Hybrid Cells
• Hypoxanthine Phosphoribosyltransferase
• Mice
• Species Specificity

PubMed Central ID

• 3082971

Digital Object Identifier (DOI)

• 10.1093/oxfordjournals.jhered.a110160

start page

• 2

end page

• 7

volume

• 77

issue

• 1

URL

• http://dx.doi.org/10.1093/oxfordjournals.jhered.a110160