Synteny mapping of four genes from the short arm of human chromosome 19 to bovine chromosome 7. Academic Article

abstract

• Four genes on the short arm of human chromosome 19 (HSA 19p) were assigned to bovine chromosome 7 (BTA 7) using a bovine x rodent somatic hybrid cell panel. These four genes were cartilage oligomeric matrix protein (COMP), lymphoblastic leukemia derived sequence 1 (LYL1), lysosomal alpha-mannosidase (MANB), and RAS oncogene family member RAB3A. Bovine sequence tagged sites were developed for the four genes and used for screening a bovine x rodent somatic cell panel. All four genes were mapped to bovine synteny group U22 (BTA 7) with a correlation coefficient of 0.901-1.000. This study confirms that the centromeric region of BTA 7 is conserved with HSA 19p.

published proceedings

• Cytogenet Cell Genet

author list (cited authors)

• Gu, Z. X., Womack, J. E., & Kirkpatrick, B. W.

citation count

• 1

complete list of authors

• Gu, ZX||Womack, JE||Kirkpatrick, BW

publication date

• January 1997

publisher

• Karger Publishers  Publisher

published in

• Cytogenetic and Genome Research  Journal

keywords

• Alpha-mannosidase
• Animals
• Cartilage
• Cartilage Oligomeric Matrix Protein
• Cattle
• Chromosome Mapping
• Chromosomes, Human, Pair 19
• Extracellular Matrix Proteins
• Genes, Ras
• Glycoproteins
• Humans
• Leukemia, Lymphoid
• Mannosidases
• Matrilin Proteins
• Sequence Tagged Sites

PubMed Central ID

• 9605858

Digital Object Identifier (DOI)

• 10.1159/000134728

start page

• 225

end page

• 227

volume

• 79

issue

• 3-4

URL

• http://dx.doi.org/10.1159/000134728