The promise of comparative genomics in mammals. Academic Article

abstract

• Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.

authors

• Andersson, Leif
• Murphy, William

published proceedings

• Science

altmetric score

• 29

author list (cited authors)

• O'Brien, S. J., Menotti-Raymond, M., Murphy, W. J., Nash, W. G., Wienberg, J., Stanyon, R., ... Marshall Graves, J. A.

citation count

• 386

complete list of authors

• O'Brien, SJ||Menotti-Raymond, M||Murphy, WJ||Nash, WG||Wienberg, J||Stanyon, R||Copeland, NG||Jenkins, NA||Womack, JE||Marshall Graves, JA

publication date

• October 1999

publisher

• American Association for the Advancement of Science (AAAS)  Publisher

published in

• Science  Journal

keywords

• Animals
• Animals, Domestic
• Base Sequence
• Chromosome Mapping
• Evolution, Molecular
• Genetic Markers
• Genome
• Genome, Human
• Humans
• Mammals
• Mutation
• Phylogeny
• Rodentia

PubMed Central ID

• 10521336

Digital Object Identifier (DOI)

• 10.1126/science.286.5439.458

start page

• 458

end page

• 481

volume

• 286

issue

• 5439

URL

• http://dx.doi.org/10.1126/science.286.5439.458