Comparative mapping of anchor loci from HSA19 to cattle chromosomes 7 and 18. Academic Article

abstract

• Six loci--CALR, EPOR, JUNB, JUND, CEA, and PRKCG--were assigned to bovine chromosomes using PCR-based hybrid somatic cell analysis. The five genes other than CALR are comparative mapping anchor loci. This study, together with the previous assignment of three anchor loci--INSR, LDLR, APOE--and four other genes--AMH, GPI, RYR1, LHB--defines the conserved synteny relationship between human chromosome 19 and cattle chromosomes 7 and 18. Genes on HSA 19p13.3-13.2 are conserved in cattle chromosome 7, while those on HSA19-q13.1-13.4 are conserved in cattle chromosome 18. In contrast, homologous genes from HSA19 are located on four different mouse chromosomes, namely MMU10, MMU8, MMU9, and MMU7. This is further evidence that syntenic conservation between cattle and human generally exceeds that observed between human and mouse.

authors

• Womack, James

published proceedings

• J Hered

author list (cited authors)

• Gao, Q., & Womack, J. E.

citation count

• 4

complete list of authors

• Gao, Q||Womack, JE

publication date

• November 1997

publisher

• Oxford University Press (OUP)  Publisher

published in

• JOURNAL OF HEREDITY  Journal

keywords

• Animals
• Calcium-Binding Proteins
• Calreticulin
• Carcinoembryonic Antigen
• Cattle
• Chromosome Mapping
• Humans
• Hybrid Cells
• Isoenzymes
• Mice
• Protein Kinase C
• Proto-Oncogene Proteins C-jun
• Receptors, Erythropoietin
• Ribonucleoproteins

PubMed Central ID

• 9419894

Digital Object Identifier (DOI)

• 10.1093/oxfordjournals.jhered.a023149

start page

• 524

end page

• 527

volume

• 88

issue

• 6

URL

• http://dx.doi.org/10.1093/oxfordjournals.jhered.a023149