Syntenic assignment of dopamine tautomerase (DCT) to bovine chromosome 12 Academic Article uri icon

abstract

  • Heterologous primers were used to amplify an exon and intron-containing segment of the bovine homologue of the human dopachrome tautomerase gene. After confirmation of homology by sequence analysis (exon sequence similarity greater than 90%), bovine-specific primers were developed for synteny mapping purposes. The dopachrome tautomerase gene was assigned to bovine chromosome 12 (BTA12) with 97% concordance to the coagulation factor 10 locus. Together with previous synteny mapping of bovine chromosome 12 genes, fms-related tyrosine kinase, esterase D and 5-hydroxytryptamine receptor 2, this assignment further indicates conservation between human chromosome 13q and bovine chromosome 12.

author list (cited authors)

  • Sun, H. S., Womack, J. E., & Kirkpatrick, B. W.

citation count

  • 0

complete list of authors

  • Sun, HS||Womack, JE||Kirkpatrick, BW

publication date

  • December 1996

publisher