Somatic cell mapping of bovine EC-SOD and SOD1L loci.
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cDNA probes of human extracellular superoxide dismutase (EC-SOD) and bovine superoxide dismutase 1 (SOD1) genes were hybridized to Southern blots containing genomic DNAs from cow-rodent somatic cell lines segregating bovine chromosomes. The SOD1 probe identified two loci: the coding locus (SOD1), which mapped to bovine U10; and a related locus (SOD1L), which mapped to U11. EC-SOD mapped to bovine U15. The mapping of EC-SOD to human chromosome 4, and our mapping of EC-SOD to U15, further defines a region of extensive syntenic conservation between humans and domestic cows.
author list (cited authors)
Gallagher, D. S., Gibbs, L. S., Shaffer, J. B., & Womack, J. E.
complete list of authors
Gallagher, DS||Gibbs, LS||Shaffer, JB||Womack, JE