Fine-mapping and construction of a bovine contig spanning the ovine callipyge locus. Academic Article uri icon


  • The callipyge (CLPG) gene was fine-mapped by linkage analysis to a 4.6-cM chromosome interval on distal ovine OAR18q, flanked by microsatellite markers IDVGA30 and OY3. The OAR18q linkage map and human HSA14q transcript map were aligned by genotyping two bovine-hamster whole-genome radiation hybrid panels with the microsatellite markers, as well as with sequences corresponding to HSA 14q genes. Using Type I loci mapping to the IDVGA30-OY3 interval as anchor points, we have constructed a 1.4-Mb bovine BAC contig containing the IDVGA30-OY3 interval. We demonstrate that the IDVGA30-OY3 interval spans approximately 770 kb and contains at least four genes: YY1, WARS, DLK1, and GTL2.

published proceedings

  • Mamm Genome

author list (cited authors)

  • Shay, T. L., Berghmans, S., Segers, K., Meyers, S., Beever, J. E., Womack, J. E., ... Cockett, N. E.

citation count

  • 21

complete list of authors

  • Shay, TL||Berghmans, S||Segers, K||Meyers, S||Beever, JE||Womack, JE||Georges, M||Charlier, C||Cockett, NE

publication date

  • February 2001