Fine-mapping and construction of a bovine contig spanning the ovine callipyge locus. Academic Article

abstract

• The callipyge (CLPG) gene was fine-mapped by linkage analysis to a 4.6-cM chromosome interval on distal ovine OAR18q, flanked by microsatellite markers IDVGA30 and OY3. The OAR18q linkage map and human HSA14q transcript map were aligned by genotyping two bovine-hamster whole-genome radiation hybrid panels with the microsatellite markers, as well as with sequences corresponding to HSA 14q genes. Using Type I loci mapping to the IDVGA30-OY3 interval as anchor points, we have constructed a 1.4-Mb bovine BAC contig containing the IDVGA30-OY3 interval. We demonstrate that the IDVGA30-OY3 interval spans approximately 770 kb and contains at least four genes: YY1, WARS, DLK1, and GTL2.

authors

• Womack, James

published proceedings

• Mamm Genome

author list (cited authors)

• Shay, T. L., Berghmans, S., Segers, K., Meyers, S., Beever, J. E., Womack, J. E., ... Cockett, N. E.

citation count

• 21

complete list of authors

• Shay, TL||Berghmans, S||Segers, K||Meyers, S||Beever, JE||Womack, JE||Georges, M||Charlier, C||Cockett, NE

publication date

• February 2001

publisher

• Springer Nature  Publisher

published in

• MAMMALIAN GENOME  Journal

keywords

• Animals
• Cattle
• Cloning, Molecular
• Contig Mapping
• Cricetinae
• Crosses, Genetic
• Genotype
• Male
• Microsatellite Repeats
• Muscle Development
• Muscle Fibers, Fast-twitch
• Muscle, Skeletal
• Proteins
• Radiation Hybrid Mapping
• Sheep

PubMed Central ID

• 11210184

Digital Object Identifier (DOI)

• 10.1007/s003350010248

start page

• 141

end page

• 149

volume

• 12

issue

• 2

URL

• http://dx.doi.org/10.1007/s003350010248