Zhang, Hua Instructional Assistant Professor

academic article

• Liang, T., Zhang, H., Xu, Q., Wang, S., Qin, C., & Lu, Y. (2019). Mutant Dentin Sialophosphoprotein Causes Dentinogenesis Imperfecta. Journal of Dental Research.  98(8), 912-919.
  
• Saiyin, W., Li, L., Zhang, H., Lu, Y., & Qin, C. (2019). Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF- and MAPK signaling pathways. BBA: Molecular Basis of Disease. 
  
• Zhang, H., Li, L., Kesterke, M. J., Lu, Y., & Qin, C (2019). High-Phosphate Diet Improved the Skeletal Development of Fam20c-Deficient Mice. Cells, Tissues, Organs: in vivo, in vitro.  208(1-2), 25-36.
  
• Liu, X., Li, N., Zhang, H., Liu, J., Zhou, N., Ran, C., ... Liu, C. (2018). Inactivation of Fam20b in the neural crest-derived mesenchyme of mouse causes multiple craniofacial defects. European Journal Of Oral Sciences.  126(5), 433-436.
  
• Jani, P., Liu, C., Zhang, H., Younes, K., Benson, M. D., & Qin, C. (2018). The role of bone morphogenetic proteins 2 and 4 in mouse dentinogenesis. Arch Oral Biol.  90, 33-39.
  
• Liu, C., Zhang, H., Jani, P., Wang, X., Lu, Y., Li, N., Xiao, J., & Qin, C. (2018). FAM20C regulates osteoblast behaviors and intracellular signaling pathways in a cell-autonomous manner. Journal of Cellular Physiology.  233(4), 3476-3486.
  
• Liu, C., Zhou, N., Wang, Y. u., Zhang, H., Jani, P., Wang, X., ... Qin, C. (2018). Abrogation of Fam20c altered cell behaviors and BMP signaling of immortalized dental mesenchymal cells. Exp Cell Res.  363(2), 188-195.
  
• Zhang, H., Xie, X., Liu, P., Liang, T., Lu, Y., & Qin, C. (2018). Transgenic expression of dentin phosphoprotein (DPP) partially rescued the dentin defects of DSPP-null mice. PLoS One.  13(4), e0195854-e0195854.
  
• Zhang, H., Jani, P., Liang, T., Lu, Y., & Qin, C. (2017). Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice. Journal of Molecular Histology.  48(2), 83-98.
  
• Liu, P., Ma, S. u., Zhang, H., Liu, C., Lu, Y., Chen, L. i., & Qin, C. (2017). Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia. Scientific Reports.  7(1), 3590.
  
• Xie, X., Liu, C., Zhang, H., Jani, P. H., Lu, Y., Wang, X., Zhang, B., & Qin, C. (2016). Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression. Scientific Reports.  6(1), 25364.
  
• Jani, P. H., Gibson, M. P., Liu, C., Zhang, H., Wang, X., Lu, Y., & Qin, C. (2016). Transgenic expression of Dspp partially rescued the long bone defects of Dmp1-null mice. Matrix Biol.  52-54, 95-112.
  
• Zhang, H., Liu, P., Wang, S., Liu, C., Jani, P., Lu, Y., & Qin, C. (2016). Transgenic expression of dentin phosphoprotein inhibits skeletal development. European Journal of Histochemistry.  60(1), 2587-54.
  
• Meng, T., Huang, Y., Wang, S., Zhang, H., Dechow, P. C., Wang, X., ... Lu, Y. (2015). Twist1 Is Essential for Tooth Morphogenesis and Odontoblast Differentiation. Journal of Biological Chemistry.  290(49), 29593-29602.
  
• Liu, C., Wang, X., Zhang, H., Xie, X., Liu, P., Liu, Y., ... Qin, C. (2015). Immortalized Mouse Floxed Fam20c Dental Papillar Mesenchymal and Osteoblast Cell Lines Retain Their Primary Characteristics. Journal of Cellular Physiology.  230(11), 2581-2587.
  
• Feng, J. Q., Zhang, H., & Qin, C. (2015). Letter to the Editor, "Osterix Regulates Tooth Root Formation in a Site-specific Manner". Journal of Dental Research.  94(9), 1326-1326.
  
• Mobley, C. G., Kuzynski, M., Zhang, H., Jani, P., Qin, C., & Napierala, D. (2015). Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation. Journal of Dental Research.  94(8), 1128-1134.
  
• Zhang, H., Jiang, Y., Qin, C., Liu, Y., Ho, S. P., & Feng, J. Q. (2015). Essential role of osterix for tooth root but not crown dentin formation. J Bone Miner Res.  30(4), 742-746.
  
• Cao, Z., Liu, R., Zhang, H., Liao, H., Zhang, Y., Hinton, R. J., & Feng, J. Q. (2015). Osterix controls cementoblast differentiation through downregulation of Wnt-signaling via enhancing DKK1 expression. International Journal of Biological Sciences.  11(3), 335-344.
  
• Chen, S., Feng, J., Zhang, H., Jia, M., Shen, Y., & Zong, Z (2014). Key role for the transcriptional factor, osterix, in spine development. Spine J.  14(4), 683-694.
  
• Cao, Z., Zhang, H., Zhou, X., Han, X., Ren, Y., Gao, T., ... Feng, J. Q (2012). Genetic evidence for the vital function of Osterix in cementogenesis. J Bone Miner Res.  27(5), 1080-1092.