selected publications academic article Liang, T., Zhang, H., Xu, Q., Wang, S., Qin, C., & Lu, Y. (2019). Mutant Dentin Sialophosphoprotein Causes Dentinogenesis Imperfecta. Journal of Dental Research. 98(8), 912-919. Saiyin, W., Li, L., Zhang, H., Lu, Y., & Qin, C. (2019). Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF- and MAPK signaling pathways. BBA: Molecular Basis of Disease. Zhang, H., Li, L., Kesterke, M. J., Lu, Y., & Qin, C (2019). High-Phosphate Diet Improved the Skeletal Development of Fam20c-Deficient Mice. Cells, Tissues, Organs: in vivo, in vitro. 208(1-2), 25-36. Liu, X., Li, N., Zhang, H., Liu, J., Zhou, N., Ran, C., ... Liu, C. (2018). Inactivation of Fam20b in the neural crest-derived mesenchyme of mouse causes multiple craniofacial defects. European Journal Of Oral Sciences. 126(5), 433-436. Jani, P., Liu, C., Zhang, H., Younes, K., Benson, M. D., & Qin, C. (2018). The role of bone morphogenetic proteins 2 and 4 in mouse dentinogenesis. Arch Oral Biol. 90, 33-39. Liu, C., Zhang, H., Jani, P., Wang, X., Lu, Y., Li, N., Xiao, J., & Qin, C. (2018). FAM20C regulates osteoblast behaviors and intracellular signaling pathways in a cell-autonomous manner. Journal of Cellular Physiology. 233(4), 3476-3486. Liu, C., Zhou, N., Wang, Y. u., Zhang, H., Jani, P., Wang, X., ... Qin, C. (2018). Abrogation of Fam20c altered cell behaviors and BMP signaling of immortalized dental mesenchymal cells. Exp Cell Res. 363(2), 188-195. Zhang, H., Xie, X., Liu, P., Liang, T., Lu, Y., & Qin, C. (2018). Transgenic expression of dentin phosphoprotein (DPP) partially rescued the dentin defects of DSPP-null mice. PLoS One. 13(4), e0195854-e0195854. Zhang, H., Jani, P., Liang, T., Lu, Y., & Qin, C. (2017). Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice. Journal of Molecular Histology. 48(2), 83-98. Liu, P., Ma, S. u., Zhang, H., Liu, C., Lu, Y., Chen, L. i., & Qin, C. (2017). Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia. Scientific Reports. 7(1), 3590. Xie, X., Liu, C., Zhang, H., Jani, P. H., Lu, Y., Wang, X., Zhang, B., & Qin, C. (2016). Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression. Scientific Reports. 6(1), 25364. Jani, P. H., Gibson, M. P., Liu, C., Zhang, H., Wang, X., Lu, Y., & Qin, C. (2016). Transgenic expression of Dspp partially rescued the long bone defects of Dmp1-null mice. Matrix Biol. 52-54, 95-112. Zhang, H., Liu, P., Wang, S., Liu, C., Jani, P., Lu, Y., & Qin, C. (2016). Transgenic expression of dentin phosphoprotein inhibits skeletal development. European Journal of Histochemistry. 60(1), 2587-54. Meng, T., Huang, Y., Wang, S., Zhang, H., Dechow, P. C., Wang, X., ... Lu, Y. (2015). Twist1 Is Essential for Tooth Morphogenesis and Odontoblast Differentiation. Journal of Biological Chemistry. 290(49), 29593-29602. Liu, C., Wang, X., Zhang, H., Xie, X., Liu, P., Liu, Y., ... Qin, C. (2015). Immortalized Mouse Floxed Fam20c Dental Papillar Mesenchymal and Osteoblast Cell Lines Retain Their Primary Characteristics. Journal of Cellular Physiology. 230(11), 2581-2587. Feng, J. Q., Zhang, H., & Qin, C. (2015). Letter to the Editor, "Osterix Regulates Tooth Root Formation in a Site-specific Manner". Journal of Dental Research. 94(9), 1326-1326. Mobley, C. G., Kuzynski, M., Zhang, H., Jani, P., Qin, C., & Napierala, D. (2015). Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation. Journal of Dental Research. 94(8), 1128-1134. Zhang, H., Jiang, Y., Qin, C., Liu, Y., Ho, S. P., & Feng, J. Q. (2015). Essential role of osterix for tooth root but not crown dentin formation. J Bone Miner Res. 30(4), 742-746. Cao, Z., Liu, R., Zhang, H., Liao, H., Zhang, Y., Hinton, R. J., & Feng, J. Q. (2015). Osterix controls cementoblast differentiation through downregulation of Wnt-signaling via enhancing DKK1 expression. International Journal of Biological Sciences. 11(3), 335-344. Chen, S., Feng, J., Zhang, H., Jia, M., Shen, Y., & Zong, Z (2014). Key role for the transcriptional factor, osterix, in spine development. Spine J. 14(4), 683-694. Cao, Z., Zhang, H., Zhou, X., Han, X., Ren, Y., Gao, T., ... Feng, J. Q (2012). Genetic evidence for the vital function of Osterix in cementogenesis. J Bone Miner Res. 27(5), 1080-1092.
education and training Ph.D. in Pharmacology/Molecular Biology & Biochemistry, Xi'an University of Posts and Telecommunications - (Xi'an, China) 2010 M.S. in Medical Pathology, Qingdao University - (Qingdao, China) 1997 M.D. in Medicine, Qingdao University - (Qingdao, China) 1994 Texas A&M Health Science Center - (College Station, Texas, United States) , Postdoctoral Training 2016
mailing address Texas A&M University College of Dentistry Biomedical Sciences 3302 Gaston Avenue Dallas, TX 75246 USA