Chaotically accelerated polymerase chain reaction by microscale Rayleigh-Bnard convection. Academic Article uri icon


  • (Figure Presented) Going with the flow: DNA replication by the polymerase chain reaction (PCR) can proceed at a greatly accelerated rate when performed in the presence of a chaotic flow induced by microscale thermal convection (see picture). The consequences of these effects sharply contradict established design rules for chemistry involving coupled flow and reaction. 2011 Wiley-VCH Verlag GmbH & Co. KGaA.

published proceedings

  • Angew Chem Int Ed Engl

author list (cited authors)

  • Muddu, R., Hassan, Y. A., & Ugaz, V. M.

citation count

  • 20

complete list of authors

  • Muddu, Radha||Hassan, Yassin A||Ugaz, Victor M

publication date

  • March 2011