Transverse electronic transport in double-stranded DNA nucleotides. Academic Article

abstract

• We calculate the transverse current through double-stranded DNA nucleotides using ab initio techniques in order to establish a protocol to recognize the type and sequence of double-stranded DNA nucleotides. The distinct current-voltage features between nucleotides are used as signatures for their characterization and sequencing. Extended bulk gold electrodes as well as extensions of the DNA backbones are tested as contacts for the electron transport, yielding currents 2 orders of magnitude larger for the former. The addition of Na or H positive counterions improves the signal levels, thus leading to a better discrimination, especially when sodium cations are added.

authors

• Seminario, Jorge

published proceedings

• J Phys Chem B

author list (cited authors)

• Jauregui, L. A., Salazar-Salinas, K., & Seminario, J. M.

citation count

• 20

complete list of authors

• Jauregui, Luis A||Salazar-Salinas, Karim||Seminario, Jorge M

publication date

• May 2009

publisher

• American Chemical Society (ACS)  Publisher

published in

• The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter  Journal

keywords

• DNA
• Electrons
• Models, Molecular
• Nucleic Acid Conformation

PubMed Central ID

• 19402724

Digital Object Identifier (DOI)

• 10.1021/jp808790j

start page

• 6230

end page

• 6239

volume

• 113

issue

• 18

URL

• http://dx.doi.org/10.1021/jp808790j