A micro-aspirator chip using vacuum expanded microchannels for high-throughput mechanical characterization of biological cells Conference Paper uri icon


  • Mechanical properties of cells can serve as biomarkers to identify cells depending on their disease states, and thus have the potential to be used in disease diagnostic applications. However, existing techniques are not capable of quantifying these properties in statistically significant quantities. To address this, we propose a high-throughput micro-aspirator chip, which can deliver, trap, and deform multiple cells simultaneously at single-cell resolution without skill-dependent micromanipulation. The mechanical property of HeLa cells was measured using the micro-aspirator chip and no dependency of HeLa cell Young's modulus on the diameter of the cells was found.

published proceedings

  • 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010

author list (cited authors)

  • Kim, W., & Han, A.

complete list of authors

  • Kim, W||Han, A

publication date

  • December 2010