An experimental and theoretical model for the passive biomechanical properties of the intact heart
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An experimental and theoretical model for the passive biomechanical properties of the intact heart is presented. Constitutive equations for passive cardiac tissue, based on first principles of continuum mechanics and incorporating the structural features of the material, are described. Results of MR imaging experiments with a canine subject demonstrate the feasibility of imaging the intact heart and implanted markers at designated phases of diastasis, while concurrently measuring ventricular pressure as a reference. Ultimately, the experimental data will serve as input to a finite element routine, coupled with a nonlinear regression algorithm, to allow the determination of the nonlinear orthotropic material parameters inherent in the model assumptions.
author list (cited authors)
Antaki, J. F., Rajagopal, K. R., Rosenthal, M. S., Vorp, D. A., Gartner, M. J., & Borovetz, H. S.