Effect of Yeast Saccharomyces cerevisiae as a Probiotic on Diet Digestibility, Fermentative Metabolites, and Composition and Functional Potential of the Fecal Microbiota of Dogs Submitted to an Abrupt Dietary Change. Academic Article uri icon


  • The aim was to evaluate the effects of yeast probiotic on diet digestibility, fermentative metabolites, and fecal microbiota of dogs submitted to dietary change. Sixteen dogs were divided into two groups of eight dogs each: control, without, and with probiotic, receiving 0.12 g/dog/day of live Saccharomyces cerevisiae yeast. The dogs were fed a lower protein and fiber diet for 21 days and then changed to a higher protein and fiber diet until day 49. Yeast supplementation did not statistically influence diet digestibility. The probiotic group had a lower fecal concentration of total biogenic amines (days 21 and 49), ammonia (day 23), and aromatic compounds and a higher fecal concentration of butyrate (p < 0.05). The probiotic group showed a lower dysbiosis index, a higher abundance (p < 0.05) of Bifidobacterium (days 35 and 49) and Turicibacter, and a lower abundance of Lactobacillus and E. coli (p < 0.05). Beta diversity demonstrated a clear differentiation in the gut microbiota between the control and probiotic groups on day 49. The control group showed upregulation in genes related to virulence factors, antibiotic resistance, and osmotic stress. The results indicated that the live yeast evaluated can have beneficial effects on intestinal functionality of dogs.

published proceedings

  • Microorganisms

altmetric score

  • 1

author list (cited authors)

  • Bastos, T. S., Souza, C., Legendre, H., Richard, N., Pilla, R., Suchodolski, J. S., ... Flix, A. P.

citation count

  • 0

complete list of authors

  • Bastos, Taís Silvino||Souza, Camilla Mariane Menezes||Legendre, Héloïse||Richard, Nadège||Pilla, Rachel||Suchodolski, Jan S||de Oliveira, Simone Gisele||Lesaux, Achraf Adib||Félix, Ananda Portella

publication date

  • February 2023