Extracellular Vesicles and Immunomodulation in Mosquitoes and Ticks Academic Article

abstract

• Extracellular vesicles are small blebs that are secreted by cells, which are lipid-rich and contain proteomic and genomic material (including small RNAs, mRNA, and plasmid DNA). These materials are delivered into recipient cells leading to a phenotypic change. Recent studies have demonstrated the secretion of extracellular vesicles by mosquito and tick cells, as well as tick salivary glands. Further, these studies suggest vesicles play a role in the transmission of vector-borne pathogens, including viruses and bacteria, and are involved in the manipulation of wound healing and immune responses. Both of these processes are key in the host response to hematophagous arthropods feeding. The role of mosquito and tick EVs in the modulation of immune responses and pathogen transmission is discussed in this entry.

authors

• Oliva Chavez, Adela

published proceedings

• Encyclopedia

altmetric score

• 2.2

author list (cited authors)

• Leal-Galvan, B., Rosario, C. A., & Chvez, A. O.

citation count

• 0

complete list of authors

• Leal-Galvan, Brenda||Rosario, Charluz Arocho||Chávez, Adela Oliva

publication date

• 2022

publisher

• MDPI  Publisher

published in

• Encyclopedia  Journal

keywords

• 31 Biological Sciences
• 3107 Microbiology
• 32 Biomedical And Clinical Sciences
• Emerging Infectious Diseases
• Genetics
• Infection
• Infectious Diseases
• Vector-borne Diseases

Digital Object Identifier (DOI)

• 10.3390/encyclopedia2020057

start page

• 873

end page

• 881

volume

• 2

issue

• 2

URL

• http://dx.doi.org/10.3390/encyclopedia2020057