Characterization of AntB, a promiscuous acyltransferase involved in antimycin biosynthesis. Academic Article uri icon


  • The in vivo and in vitro characterization of AntB, a dedicated acyltransferase encoded in the antimycin biosynthetic gene cluster, which catalyzes the C-8 acyloxy formation is reported. It is demonstrated that AntB has broad substrate specificity toward both the acyl substrate and the acyl carrier and produces more antimycin analogues with varying C-8 acyloxy moieties.

published proceedings

  • Org Lett

author list (cited authors)

  • Sandy, M., Zhu, X., Rui, Z., & Zhang, W.

complete list of authors

  • Sandy, Moriah||Zhu, Xuejun||Rui, Zhe||Zhang, Wenjun

publication date

  • July 2013