Ultrasound guidance allows accurate needle placement and aspiration from small joints in patients with early inflammatory arthritis. Academic Article uri icon


  • OBJECTIVES: To compare the accuracy of palpation-guided and high frequency ultrasound-guided needle placement in small joints and to develop a technique to obtain synovial fluid from these joints for diagnosis and research. METHODS: The accuracy of needle placement during palpation-guided proximal interphalangeal (PIP) or metacarpophalangeal (MCP) joint injection was assessed. This was compared with the accuracy of ultrasound-guided needle placement. A joint lavage technique was developed to obtain synovial fluid from these joints. RESULTS: Needle positioning was intra-articular in 59% of palpation-guided injections (6/12 PIP and 4/5 MCP joints). No fluid could be aspirated prior to injection. With ultrasound guidance, initial needle placement was intra-articular in 96% of cases (24/26 PIP and 27/27 MCP joints). Synovial fluid cells were lavaged from 63% of joints (19/25 PIP and 14/27 MCP joints). In only one case was a large effusion seen and this was aspirated directly. CONCLUSIONS: The use of high frequency ultrasound to guide needle placement within a small joint allows for significantly greater accuracy than a palpation-guided approach. When followed by lavage, synovial fluid cells and diluted synovial fluid can be obtained from the majority of small joints. This has important clinical and research implications.

published proceedings

  • Rheumatology (Oxford)

author list (cited authors)

  • Raza, K., Lee, C. Y., Pilling, D., Heaton, S., Situnayake, R. D., Carruthers, D. M., ... Salmon, M.

citation count

  • 153

complete list of authors

  • Raza, K||Lee, CY||Pilling, D||Heaton, S||Situnayake, RD||Carruthers, DM||Buckley, CD||Gordon, C||Salmon, M

publication date

  • August 2003