Programmable nanomedicine: synergistic and sequential drug delivery systems. Academic Article uri icon


  • Recent developments in nanomedicine for the cancer therapy have enabled programmable delivery of therapeutics by exploiting the stimuli-responsive properties of nanocarriers. These therapeutic systems were designed with the relevant chemical and physical properties that respond to different triggers for enhanced anticancer efficacy, including the reduced development of drug-resistance, lower therapeutic dose, site-specific transport, and spatiotemporally controlled release. This minireview discusses the current advances in programmable nanocarriers for cancer therapy with particular emphasis on synergistic and sequential drug delivery systems.

published proceedings

  • Nanoscale

altmetric score

  • 3

author list (cited authors)

  • Pacardo, D. B., Ligler, F. S., & Gu, Z.

citation count

  • 120

complete list of authors

  • Pacardo, Dennis B||Ligler, Frances S||Gu, Zhen

publication date

  • February 2015