Surface modification and biomolecule immobilization on polymer spheres for biosensing applications. Chapter uri icon


  • Microspheres and nanospheres are being used in many of today's biosensing applications for automated sample processing, flow cytometry, signal amplification in microarrays, and labeling in multiplexed analyses. The surfaces of the spheres/particles need to be modified with proteins and other biomolecules to be used in these sensing applications. This chapter contains protocols to modify carboxyl- and amine-coated polymer spheres with proteins and peptides.

author list (cited authors)

  • Taitt, C. R., Shriver-Lake, L. C., Anderson, G. P., & Ligler, F. S.

citation count

  • 15

complete list of authors

  • Taitt, Chris R||Shriver-Lake, Lisa C||Anderson, George P||Ligler, Frances S

Book Title


publication date

  • January 2011