Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery.

abstract

• Self-folded redox/acid dual-responsive nanocarriers (RAD-NCs) are developed for physiologically triggered delivery of anticancer drugs. The evidenced redox/acid responsiveness, facile decoration of ligands, and active tumor-targeting capability of RAD-NCs suggest their potential as a promising formulation for tumor-targeted chemotherapy.

authors

• Ligler, Frances

published proceedings

• Chem Commun (Camb)

author list (cited authors)

• Lu, Y., Mo, R., Tai, W., Sun, W., Pacardo, D. B., Qian, C., ... Gu, Z.

complete list of authors

• Lu, Yue||Mo, Ran||Tai, Wanyi||Sun, Wujin||Pacardo, Dennis B||Qian, Chenggen||Shen, Qundong||Ligler, Frances S||Gu, Zhen

publisher

• Royal Society of Chemistry (RSC)  Publisher

published in

• Chemical Communications  Journal

keywords

• Antineoplastic Agents
• Cell Survival
• Doxorubicin
• Drug Carriers
• Folic Acid
• Glutathione
• Hela Cells
• Humans
• Nanoparticles
• Oxidation-Reduction
• Peptides
• Polyethylene Glycols

PubMed Central ID

• 25331017

Digital Object Identifier (DOI)

• 10.1039/c4cc07004f

start page

• 15105

end page

• 15108

volume

• 50

issue

• 95