Reversible cobalt ion binding to imidazole-modified nanopipettes. Academic Article

abstract

• In this report, we demonstrate that quartz nanopipettes modified with an imidazole-terminated silane respond to metal ions (Co(2+)) in solution. The response of nanopipettes is evaluated through examination of the ion current rectification ratio. When nanopipettes are cycled between solutions of different pH, adsorbed Co(2+) can be released from the nanopipette surface, to regenerate binding sites of the nanopipette. These results demonstrate that rectification-based sensing strategies for nanopore sensors can benefit from selection of recognition elements with intermediate binding affinities, such that reversible responses can be attained.

authors

• Baker, Lane

published proceedings

• Anal Chem

altmetric score

• 6

author list (cited authors)

• Sa, N., Fu, Y., & Baker, L. A.

citation count

• 60
• 61

complete list of authors

• Sa, Niya||Fu, Yaqin||Baker, Lane A

publication date

• December 2010

publisher

• American Chemical Society (ACS)  Publisher

published in

• Analytical Chemistry  Journal

keywords

• Binding Sites
• Cations
• Chemistry Techniques, Analytical
• Cobalt
• Equipment And Supplies
• Equipment Design
• Imidazoles
• Nanopores
• Nanostructures
• Silanes

PubMed Central ID

• 21090777

Digital Object Identifier (DOI)

• 10.1021/ac102619j

start page

• 9963

end page

• 9966

volume

• 82

issue

• 24

URL

• http://dx.doi.org/10.1021/ac102619j