Biphasic-Scanning Ion Conductance Microscopy. Academic Article uri icon


  • A concentration gradient driven imaging mechanism is described for scanning ion conductance microscopy (SICM). Two different solution phases, one filling a double-barrel pipet and one in the bath, are used to afford probe control and imaging under nonstandard SICM conditions. Under these conditions, solutions with no added electrolyte can be utilized as the bath solution. Further, both positive and negative feedback modes are exhibited as the probe approaches the surface. We term this method biphasic-SICM (BP-SICM). Technical details of implementing BP-SICM and operational principles are described herein.

published proceedings

  • Anal Chem

altmetric score

  • 3.6

author list (cited authors)

  • Choi, M., & Baker, L. A.

citation count

  • 8

complete list of authors

  • Choi, Myunghoon||Baker, Lane A

publication date

  • October 2018