Application of optogenetics-mediated motor cortex stimulation in the treatment of chronic neuropathic pain. Academic Article uri icon

abstract

  • Motor cortex stimulation provides an alternate approach for intractable pain treatment. Optogenetic manipulation can produce gain- or loss-of-function in specific type of cells following light application. This state-of-the-art technology may be used in motor cortex stimulation to produce circuit-specific neuromodulation and regulate neuronal activities in motor cortex, thereby treating pain in the clinic. Here, we discuss the principle of optogenetics-mediated motor cortex stimulation and discuss its potential application in the treatment of chronic neuropathic pain.

published proceedings

  • J Transl Sci

author list (cited authors)

  • Liu, S., & Tao, F.

complete list of authors

  • Liu, Sufang||Tao, Feng

publication date

  • January 2016