Application of optogenetics-mediated motor cortex stimulation in the treatment of chronic neuropathic pain. Academic Article

abstract

• Motor cortex stimulation provides an alternate approach for intractable pain treatment. Optogenetic manipulation can produce gain- or loss-of-function in specific type of cells following light application. This state-of-the-art technology may be used in motor cortex stimulation to produce circuit-specific neuromodulation and regulate neuronal activities in motor cortex, thereby treating pain in the clinic. Here, we discuss the principle of optogenetics-mediated motor cortex stimulation and discuss its potential application in the treatment of chronic neuropathic pain.

authors

• Liu, Sufang

published proceedings

• J Transl Sci

author list (cited authors)

• Liu, S., & Tao, F.

citation count

• 5

complete list of authors

• Liu, Sufang||Tao, Feng

publication date

• January 2016

publisher

• Open Access Text  Publisher

published in

• n2059-268XISSN  Journal

keywords

• 32 Biomedical And Clinical Sciences
• 3209 Neurosciences
• Chronic Pain
• Genetics
• Neurodegenerative
• Neurological
• Neurosciences
• Pain Research
• Peripheral Neuropathy
• Rehabilitation

Digital Object Identifier (DOI)

• 10.15761/JTS.1000153

start page

• 286

end page

• 288

volume

• 2

issue

• 5

URL

• http://dx.doi.org/10.15761/jts.1000153