Functions and targets of let-7 micro rnas Patent uri icon


  • The present invention concerns methods and compositions for treating or assessing treatment of diseases related to mis-expression of genes or genetic pathways that can be modulated by let-7. Methods may include evaluating patients for genes or genetic pathways modulated by let-7, and/or using an expression profile to assess the condition of a patient or treating the patient with an appropriate miRNA.

author list (cited authors)

  • Johnson, C. D., Byron, M. W., Bader, A. G., Slack, F. J., Brown, D., Ovcharenko, D., & Kelnar, K.

complete list of authors

  • Johnson, Charles D||Byron, Mike W||Bader, Andreas G||Slack, Frank J||Brown, David||Ovcharenko, Dmitriy||Kelnar, Kevin

publication date

  • January 2012