Thioether binding mediates monofunctional platinum antitumor reagents to trans configuration in DNA interactions. Academic Article uri icon


  • Methionine binding converts monofunctional platinum antitumor agents to trans configuration adducts in the reaction with DNA, which suggests the correlation of two classes of platinum complexes in the antitumor mechanism.

published proceedings

  • Chem Commun (Camb)

author list (cited authors)

  • Ma, G., Min, Y., Huang, F., Jiang, T., & Liu, Y.

complete list of authors

  • Ma, Guolin||Min, Yuanzeng||Huang, Fan||Jiang, Tao||Liu, Yangzhong

publication date

  • October 2010