Selective targeting of biting females to control mosquito-borne infectious diseases. Academic Article

abstract

• Mosquitoes are vectors for a number of infectious diseases. Only females feed on blood to provision for their embryos and, in doing so, transmit pathogens to the associated vertebrate hosts. Therefore, sex is an important phenotype in the context of genetic control programs, both for sex separation in the rearing facilities to avoid releasing biting females and for ways to distort the sex ratio towards nonbiting males. We review recent progress in the fundamental knowledge of sex determination and sex chromosomes in mosquitoes and discuss new methods to achieve sex separation and sex ratio distortion to help control mosquito-borne infectious diseases. We conclude by suggesting a few critical areas for future research.

authors

• Adelman, Zachary

published proceedings

• Trends Parasitol

altmetric score

• 5.2

author list (cited authors)

• Kojin, B. B., Compton, A., Adelman, Z. N., & Tu, Z.

citation count

• 0

complete list of authors

• Kojin, Bianca B||Compton, Austin||Adelman, Zach N||Tu, Zhijian

publication date

• January 2022

publisher

• Elsevier  Publisher

published in

• n1471-4922ISSN  Journal

keywords

• Aedes
• Animals
• Culicidae
• Female
• Gene-drive
• Homomorphic Sex Chromosomes
• Male
• Meiotic Drive
• Mosquito Control
• Mosquito Vectors
• Sex Determination
• Sterile Insect Technique
• Vector Borne Diseases
• X-shredder

Digital Object Identifier (DOI)

• 10.1016/j.pt.2022.05.012

start page

• 791

end page

• 804

volume

• 38

issue

• 9

URL

• http://dx.doi.org/10.1016/j.pt.2022.05.012