Complete Nucleotide Sequence, Genome Organization, and Comparative Genomic Analyses of Citrus Yellow-Vein Associated Virus (CYVaV). Academic Article uri icon

abstract

  • Citrus yellow-vein disease (CYVD) was first reported in California in 1957. We now report that CYVD is associated with a virus-like agent, provisionally named citrus yellow-vein associated virus (CYVaV). The CYVaV RNA genome has 2,692 nucleotides and codes for two discernable open reading frames (ORFs). ORF1 encodes a protein of 190 amino acid (aa) whereas ORF2 is presumably generated by a -1 ribosomal frameshifting event just upstream of the ORF1 termination signal. The frameshift product (717 aa) encodes the RNA-dependent RNA polymerase (RdRp). Phylogenetic analyses suggest that CYVaV is closely related to unclassified virus-like RNAs in the family Tombusviridae. Bio-indexing and RNA-seq experiments indicate that CYVaV can induce yellow vein symptoms independently of known citrus viruses or viroids.

published proceedings

  • Front Microbiol

altmetric score

  • 40.93

author list (cited authors)

  • Kwon, S., Bodaghi, S., Dang, T., Gadhave, K. R., Ho, T., Osman, F., ... Vidalakis, G.

citation count

  • 10

complete list of authors

  • Kwon, Sun-Jung||Bodaghi, Sohrab||Dang, Tyler||Gadhave, Kiran R||Ho, Thien||Osman, Fatima||Al Rwahnih, Maher||Tzanetakis, Ioannis E||Simon, Anne E||Vidalakis, Georgios

publication date

  • January 2021