Classical and operant conditioning differentially modify the intrinsic properties of an identified neuron.

abstract

• A long-standing debate in neuroscience is whether classical and operant conditioning are mechanistically similar or distinct. The feeding behavior of Aplysia provides a model system suitable for addressing this question. Here we report that classical and operant conditioning of feeding behavior differentially modify the intrinsic excitability of neuron B51, a critical element for the expression of the feeding response, thus revealing that these two forms of associative learning differ at the cellular level.

authors

• Baxter, Douglas

published proceedings

• Nat Neurosci

altmetric score

• 4

author list (cited authors)

• Lorenzetti, F. D., Mozzachiodi, R., Baxter, D. A., & Byrne, J. H.

citation count

• 75

complete list of authors

• Lorenzetti, Fred D||Mozzachiodi, Riccardo||Baxter, Douglas A||Byrne, John H

publication date

• January 2006

publisher

• Springer Nature  Publisher

published in

• Nature Neuroscience  Journal

keywords

• Animals
• Aplysia
• Appetite
• Conditioning, Classical
• Conditioning, Operant
• Evoked Potentials
• Ganglia, Invertebrate
• Neurons

PubMed Central ID

• 16311590

Digital Object Identifier (DOI)

• 10.1038/nn1593

start page

• 17

end page

• 19

volume

• 9

issue

• 1

URL

• http://dx.doi.org/10.1038/nn1593