Neuronal population activity dynamics reveal a low-dimensional signature of operant learning in Aplysia. uri icon

abstract

  • Learning engages a high-dimensional neuronal population space spanning multiple brain regions. However, it remains unknown whether it is possible to identify a low-dimensional signature associated with operant conditioning, a ubiquitous form of learning in which animals learn from the consequences of behavior. Using single-neuron resolution voltage imaging, here we identify two low-dimensional motor modules in the neuronal population underlying Aplysia feeding. Our findings point to a temporal shift in module recruitment as the primary signature of operant learning. Our findings can help guide characterization of learning signatures in systems in which only a smaller fraction of the relevant neuronal population can be monitored.

published proceedings

  • Commun Biol

altmetric score

  • 1.6

author list (cited authors)

  • Costa, R. M., Baxter, D. A., & Byrne, J. H.

citation count

  • 2

complete list of authors

  • Costa, Renan M||Baxter, Douglas A||Byrne, John H

publication date

  • January 2022