Directed evolution of orthogonal ligand specificity in a single scaffold.
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author list (cited authors)
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McLachlan, M. J., Chockalingam, K., Lai, K. C., & Zhao, H.
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McLachlan, Michael J||Chockalingam, Karuppiah||Lai, Ka Chun||Zhao, Huimin
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Directed Molecular Evolution
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Estradiol
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Estrogen Receptor Alpha
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Gene Expression
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Humans
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Ligands
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Mutagenesis
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Phenylglyoxal
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Protein Structure, Tertiary
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Thiazoles
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Two-Hybrid System Techniques
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http://dx.doi.org/10.1002/anie.200903413