Acetylation of Core Histones Causes the Unfolding of 30 nm Chromatin Fiber: Analysis by Agarose Gel Electrophoresis Academic Article uri icon

abstract

  • In the present work it was directly demonstrated that increased acetylation level of histones causes the decompactization of 30 nm chromatin fiber, as revealed by low-percentage agarose gel electrophoresis. In the light of obtained results the possible molecular mechanism of the decompactization of acetylated fiber is discussed.

author list (cited authors)

  • Krajewski, W. A., Panin, V. M., & Razin, S. V.

citation count

  • 9

publication date

  • October 1993