Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. Academic Article uri icon

abstract

  • A scientific evaluation was made of the mechanisms of action of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. Distinction is made between the aryl-hydrocarbon (Ah) receptor-mediated and non-Ah receptor-mediated toxic responses. Special attention is paid to the applicability of the toxic equivalency factor (TEF) concept.

published proceedings

  • Eur J Pharmacol

altmetric score

  • 6

author list (cited authors)

  • Ahlborg, U. G., Brouwer, A., Fingerhut, M. A., Jacobson, J. L., Jacobson, S. W., Kennedy, S. W., ... Rappe, C.

citation count

  • 170

complete list of authors

  • Ahlborg, UG||Brouwer, A||Fingerhut, MA||Jacobson, JL||Jacobson, SW||Kennedy, SW||Kettrup, AA||Koeman, JH||Poiger, H||Rappe, C

publication date

  • December 1992