Fluorescent PARP Inhibitors Applied To Intracranial Glioblastoma: Accumulation and Persistence In Vivo. Academic Article uri icon

abstract

  • Rucaparib-containing fluorescent probes (1-3) inhibit PARP1 in cell models. One of these (1) was tested in a murine model and shown to permeate into implanted intracranial glioblastoma tumors and persist there for at least 24 h.

published proceedings

  • ACS Med Chem Lett

altmetric score

  • 1

author list (cited authors)

  • Gao, Z., Yang, Z., Li, Z., & Burgess, K.

citation count

  • 0

complete list of authors

  • Gao, Zhe||Yang, Zhen||Li, Zheng||Burgess, Kevin

publication date

  • June 2022