HR job title
- Associate Professor
- Contact Info
- 9794369709
- Websites
- ORCiD
- 0000-0003-3404-1428
Case, Adam Associate Professor
Positions
- Associate Professor, Medical Physiology, College of Medicine
- Associate Professor, Psychiatry and Behavioral Sciences, College of Medicine
Redox signaling is vital for proper immune system function, yet this area of research is understudied. My graduate career focused on the role of mitochondrial superoxide in T-lymphocyte development. I transitioned this expertise into my postdoctoral training where I examined the role of redox signaling in T-lymphocytes during the pathogenesis of cardiovascular disease. As an independent investigator, I have extended this work to identify the contribution of the immune system and redox signaling to different pathological states of psychological trauma and stress. With this, I am investigating the redox, metabolic, and epigenetic mechanisms that may affect immune cell function and potentiate psychological trauma-mediated inflammatory diseases.
Research Areas
- Overview
- Publications
- Teaching
- Background
- Contact
- Other
- View All
Overview
Publications
selected publications
-
academic article
-
Lauten, T. H., Elkhatib, S. K., Natour, T., Reed, E. C., Jojo, C. N., & Case, A. J.
(2024).
Beta-adrenergic signaling and T-lymphocyte-produced catecholamines are necessary for interleukin 17A synthesis. 2024.06.05.597633.
-
Lauten, T. H., Natour, T., & Case, A. J.
(2024).
Innate and adaptive immune system consequences of post-traumatic stress disorder. Autonomic Neuroscience: Basic and Clinical.
252, 103159-103159.
-
Bekhbat, M., Drake, J., Reed, E. C., Lauten, T. H., Natour, T., Vladimirov, V. I., & Case, A. J.
(2023).
Repeated social defeat stress leads to immunometabolic shifts in innate immune cells of the spleen. Brain, Behavior, and Immunity - Health.
34, 100690-100690.
-
Dietz, S. M., Schantell, M., Spooner, R. K., Sandal, M. E., Mansouri, A., Arif, Y., ... Wilson, T. W.
(2023).
Elevated CRP and TNF- levels are associated with blunted neural oscillations serving fluid intelligence. Brain, Behavior, and Immunity.
114, 430-437.
-
Yadav, S. K., Ahmad, R., Moshfegh, C. M., Sankarasubramanian, J., Joshi, V., Elkhatib, S. K., ... Singh, A. B.
(2023).
Repeated Social Defeat Stress Induces an Inflammatory Gut Milieu by Altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis. 3(4), 824-836.
-
Moshfegh, C. M., Elkhatib, S. K., Watson, G. F., Drake, J., Taylor, Z. N., Reed, E. C., ... Case, A. J.
(2023).
S100a9 Protects Against the Effects of Repeated Social Defeat Stress. 3(4), 919-929.
-
Lauten, T., Reed, E., Elkhatib, S., Moshfegh, C., Clopp, A., & Case, A.
(2023).
Neuropeptide Y potentiates T-Lymphocyte inflammation after psychological trauma. Physiology.
38(S1), 5728219.
-
Yadav, S. K., Ahmad, R., Moshfegh, C. M., Jagadesan, S., Elkhatib, S. K., Talmon, G., ... Singh, A. B.
(2023).
Sa1625 REPEATED SOCIAL DEFEAT STRESS INDUCES AN INFLAMMATORY GUT MILIEU BY COMPROMISING THE MUCOSAL BARRIER INTEGRITY AND ALTERING GUT MICROBIOTA HOMEOSTASIS. Gastroenterology.
164(6), s-411.
-
Reed, E. C., & Case, A. J.
(2023).
Defining the nuanced nature of redox biology in post-traumatic stress disorder. Frontiers in Physiology.
14, 1130861.
-
Moore, T. A., & Case, A. J.
(2022).
Cytokine levels throughout the perinatal period. The Journal of Maternal-Fetal and Neonatal Medicine.
35(25), 5513-5519.
-
Reed, E., Lauten, T., Clopp, A., Moshfegh, C., Elkhatib, S., & Case, A.
(2022).
Mitochondrial Regulation of Inflammation after Psychological Trauma. Free Radical Biology and Medicine.
192, 33-34.
-
Costanzo-Garvey, D. L., Case, A. J., Watson, G. F., Alsamraae, M., Chatterjee, A., Oberley-Deegan, R. E., ... Cook, L. M.
(2022).
Prostate cancer addiction to oxidative stress defines sensitivity to anti-tumor neutrophils. Clinical and Experimental Metastasis.
39(4), 641-659.
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2022).
T-lymphocyte tyrosine hydroxylase regulates TH17 T-lymphocytes during repeated social defeat stress. 104, 18-28.
-
Rana, S., Kour, S., Kizhake, S., King, H. M., Mallareddy, J. R., Case, A. J., Huxford, T., & Natarajan, A.
(2022).
Dimers of isatin derived -methylene--butyrolactone as potent anti-cancer agents. Bioorganic and Medicinal Chemistry Letters.
65, 128713-128713.
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2021).
T-lymphocyte tyrosine hydroxylase controls TH17 polarization during repeated social defeat stress. Brain, Behavior, and Immunity.
98, 14-15.
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., Schwab, A. D., Katsurada, K., Patel, K. P., & Case, A. J.
(2021).
Splenic denervation attenuates repeated social defeat stress-induced T-lymphocyte inflammation. 1(3), 190-200.
-
Spooner, R. K., Taylor, B. K., Moshfegh, C. M., Ahmad, I. M., Dyball, K. N., Emanuel, K., ... Zimmerman, M. C.
(2021).
Neuroinflammatory profiles regulated by the redox environment predicted cognitive dysfunction in people living with HIV: A cross-sectional study. EBioMedicine.
70, 103487-103487.
-
Moshfegh, C., Elkhatib, S., Watson, G., & Case, A.
(2021).
Repeated Social Defeat Stress Leads to Pro-Inflammatory T-Lymphocytes via Dendritic Cell Priming. Biological Psychiatry.
89(9), s387-S387.
-
Elkhatib, S., Moshfegh, C., Watson, G., Katsurada, K., Patel, K., & Case, A.
(2021).
Sympathetic Nerves Control Splenic T-Lymphocyte Inflammation and the Mitochondrial Redox Environment During Repeated Social Defeat Stress. Biological Psychiatry.
89(9), s89-s90.
-
Moshfegh, C. M., & Case, A. J.
(2021).
The Redox-Metabolic Couple of T Lymphocytes: Potential Consequences for Hypertension. Antioxidants and Redox Signaling.
34(12), 915-935.
-
Elkhatib, S. K., Ross, D. A., & Case, A. J.
(2021).
A Forgotten Rose: Embracing the Complexity of Neuroimmune Function. Biological Psychiatry.
89(5), e21-e23.
-
Place, T. L., Domann, F. E., & Case, A. J.
(2021).
Corrigendum to "Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research" [Free Radic. Biol. Med. 113 (2017) 311-322]. Free Radical Biology and Medicine.
162, 180-180.
-
Daseke, M. J., Chalise, U., Becirovic-Agic, M., Salomon, J. D., Cook, L. M., Case, A. J., & Lindsey, M. L.
(2021).
Neutrophil signaling during myocardial infarction wound repair. Cellular Signalling.
77, 109816-109816.
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2020).
Peripheral inflammation is strongly linked to elevated zero maze behavior in repeated social defeat stress. Brain, Behavior, and Immunity.
90, 279-285.
-
Moshfegh, C., Elkhatib, S., Watson, G., & Case, A.
(2020).
Redox-Regulated Calprotectin Potentiates Psychological Trauma Induced Pro-Inflammatory T-Lymphocyte Differentiation. Free Radical Biology and Medicine.
159, s45-s46.
-
Dickinson, K., Case, A. J., Kupzyk, K., & Saligan, L.
(2020).
Exploring Biologic Correlates of Cancer-Related Fatigue in Men With Prostate Cancer: Cell Damage Pathways and Oxidative Stress. Biological Research for Nursing.
22(4), 514-519.
-
Costanzo-Garvey, D. L., Keeley, T., Case, A. J., Watson, G. F., Alsamraae, M., Yu, Y., ... Cook, L. M.
(2020).
Neutrophils are mediators of metastatic prostate cancer progression in bone. Cancer Immunology Immunotherapy.
69(6), 1113-1130.
-
Elkhatib, S., Moshfegh, C., Watson, G., & Case, A.
(2020).
Neuroimmune Contributions to T-Lymphocyte-Driven Inflammation in a Preclinical Model of Post-Traumatic Stress Disorder. Biological Psychiatry.
87(9), s315-S315.
-
Moore, T. A., Samson, K., Ahmad, I. M., Case, A. J., & Zimmerman, M. C.
(2020).
Oxidative Stress in Pregnant Women Between 12 and 20 Weeks of Gestation and Preterm Birth. Nursing Research.
69(3), 244-248.
-
Moshfegh, C., Elkhatib, S., Watson, G., & Case, A.
(2020).
Psychological Trauma-Induced Calprotectin Potentiates Pro-Inflammatory T-Lymphocyte Differentiation and Memory Formation. Biological Psychiatry.
87(9), s327-S327.
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2020).
Neuroimmune Contributions to TlymphocyteDriven Inflammation in a Preclinical Model of Posttraumatic Stress Disorder (PTSD). 34(S1), 1-1.
-
Moshfegh, C. M., Collins, C. W., Gunda, V., Vasanthakumar, A., Cao, J. Z., Singh, P. K., Godley, L. A., & Case, A. J.
(2019).
Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes. Redox Biology.
27, 101141-101141.
-
Maloley, P. M., England, B. R., Sayles, H., Thiele, G. M., Michaud, K., Sokolove, J., ... Mikuls, T. R.
(2019).
Post-traumatic stress disorder and serum cytokine and chemokine concentrations in patients with rheumatoid arthritis. Seminars in Arthritis and Rheumatism.
49(2), 229-235.
-
Zimmerman, M. C., & Case, A. J.
(2019).
Redox biology in physiology and disease. Redox Biology.
27, 101267-101267.
-
Basu, U., Case, A. J., Liu, J., Tian, J., Li, Y., & Zimmerman, M. C.
(2019).
Redox-sensitive calcium/calmodulin-dependent protein kinase II in angiotensin II intra-neuronal signaling and hypertension. Redox Biology.
27, 101230-101230.
-
Elkhatib, S. K., & Case, A. J.
(2019).
Autonomic regulation of T-lymphocytes: Implications in cardiovascular disease. Pharmacological Research.
146, 104293-104293.
-
Moshfegh, C., Elkhatib, S., & Case, A.
(2019).
S21. Identification of a Novel T-Lymphocyte Inflammatory Protein in Psychological Stress-Induced Hypertension. Biological Psychiatry.
85(10), s304-S304.
-
Case, A. J., Moshfegh, C. M., & Elkhatib, S. M.
(2019).
Identification of a Novel Tlymphocyte Inflammatory Protein in Psychological Stress Induced Hypertension. 33(S1), 836.2-836.2.
-
Adam, R. J., Xia, Z., Pravoverov, K., Hong, J., Case, A. J., Schultz, H. D., ... Wang, H.
(2019).
Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure. American Journal of Physiology. Heart and Circulatory Physiology.
316(4), H862-H872.
-
Djalilova, D. M., Schulz, P. S., Berger, A. M., Case, A. J., Kupzyk, K. A., & Ross, A. C.
(2019).
Impact of Yoga on Inflammatory Biomarkers: A Systematic Review. Biological Research for Nursing.
21(2), 198-209.
-
Moore, T. A., Case, A. J., Mathews, T. L., Epstein, C. M., Kaiser, K. L., & Zimmerman, M. C.
(2019).
Interleukin-17A and Chronic Stress in Pregnant Women at 24-28 Weeks Gestation. Nursing Research.
68(2), 167-173.
-
Moshfegh, C. M., Elkhatib, S. K., Collins, C. W., Kohl, A. J., & Case, A. J.
(2019).
Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress. Frontiers in Behavioral Neuroscience.
13, 103.
-
Ahmad, I. M., Abdalla, M. Y., Moore, T. A., Bartenhagen, L., Case, A. J., & Zimmerman, M. C.
(2019).
Healthcare Workers Occupationally Exposed to Ionizing Radiation Exhibit Altered Levels of Inflammatory Cytokines and Redox Parameters. Antioxidants.
8(1), 12-12.
-
Ahmad, I., Abdalla, M., Moore, T., Bartenhagen, L., Case, A., & Zimmerman, M.
(2018).
230 Elevated pro-inflammatory cytokines in healthcare workers occupationally exposed to ionizing radiation. Free Radical Biology and Medicine.
128, s100-S100.
-
Moshfegh, C., Elkhatib, S., Collins, C., Kohl, A., & Case, A.
(2018).
37 Psychological stress-mediated hypertension is regulated via redox-signaling in T-lymphocytes. Free Radical Biology and Medicine.
128, s33-S33.
-
Moshfegh, C. M., Collins, C. W., Kohl, A. J., Elkhatib, S., & Case, A. J.
(2018).
Abstract 023: Redox-Driven T-Lymphocyte Inflammation Sensitizes Mice to Psychological Stress-Mediated Hypertension. HYPERTENSION.
72(Suppl_1),
-
Price, M. E., Case, A. J., Pavlik, J. A., DeVasure, J. M., Wyatt, T. A., Zimmerman, M. C., & Sisson, J. H.
(2018).
S-nitrosation of protein phosphatase 1 mediates alcohol-induced ciliary dysfunction. Scientific Reports.
8(1), 9701.
-
Case, A. J., Collins, C. W., Kohl, A. J., Moshfegh, C. M., & Elkhatib, S.
(2018).
RedoxDriven Lymphocyte Inflammation Sensitizes Mice to Psychological StressMediated Hypertension. 32(S1), 737.1-737.1.
-
Place, T. L., Domann, F. E., & Case, A. J.
(2017).
Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research. Free Radical Biology and Medicine.
113, 311-322.
-
Case, A. J.
(2017).
On the Origin of Superoxide Dismutase: An Evolutionary Perspective of Superoxide-Mediated Redox Signaling. Antioxidants.
6(4), 82-82.
-
Case, A. J., Tian, J., & Zimmerman, M. C.
(2017).
Increased mitochondrial superoxide in the brain, but not periphery, sensitizes mice to angiotensin II-mediated hypertension. Redox Biology.
11, 82-90.
-
Price, M. E., Case, A. J., Zimmerman, M. C., Wyatt, T. A., & Sisson, J. H.
(2017).
Oxidation of airway cilia localized protein phosphatase 1 drives alcohol-induced ciliary dysfunction. ALCOHOL.
59, 74-74.
-
Collister, J. P., Hartnett, C., Mayerhofer, T., Nahey, D., Stauthammer, C., Krger, M., ... Zimmerman, M. C.
(2016).
Overexpression of copper/zinc superoxide dismutase in the median preoptic nucleus improves cardiac function after myocardial infarction in the rat. 43(10), 960-966.
-
Case, A. J., & Zimmerman, M. C.
(2016).
Sympathetic-mediated activation versus suppression of the immune system: consequences for hypertension. Journal of Physiology.
594(3), 527-536.
-
Case, A. J., Agraz, D., Ahmad, I. M., & Zimmerman, M. C.
(2016).
Low-Dose Aronia melanocarpa Concentrate Attenuates Paraquat-Induced Neurotoxicity. Oxidative Medicine and Cellular Longevity.
2016, 5296271-11.
-
Case, A. J., Roessner, C. T., Tian, J., & Zimmerman, M. C.
(2016).
Mitochondrial Superoxide Signaling Contributes to Norepinephrine-Mediated T-Lymphocyte Cytokine Profiles. PLoS ONE.
11(10), e0164609-e0164609.
-
Wang, H., Case, A. J., Wang, W., Mueller, P. J., & Smith, S. A.
(2016).
Redox Signaling and Neural Control of Cardiovascular Function. Oxidative Medicine and Cellular Longevity.
2016, 7086018-2.
-
Case, A. J., & Zimmerman, M. C.
(2015).
64 Inverse Regulatory Effects of Mitochondrial Superoxide in Resting and Activated T-Lymphocytes. Free Radical Biology and Medicine.
87, s39-S39.
-
Case, A. J., Tian, J., & Zimmerman, M. C.
(2015).
Abstract 120: Increased Mitochondrial Superoxide in the Brain, but not Periphery, Sensitizes Mice to Angiotensin II-Mediated Hypertension. HYPERTENSION.
66(suppl_1),
-
O'Leary, B. R., Fath, M. A., Bellizzi, A. M., Hrabe, J. E., Button, A. M., Allen, B. G., ... Mezhir, J. J.
(2015).
Loss of SOD3 (EcSOD) Expression Promotes an Aggressive Phenotype in Human Pancreatic Ductal Adenocarcinoma. CLINICAL CANCER RESEARCH.
21(7), 1741-1751.
-
Case, A. J., & Zimmerman, M. C.
(2015).
Redox-regulated suppression of splenic T-lymphocyte activation in a model of sympathoexcitation. HYPERTENSION.
65(4), 916-923.
-
Basu, U., Seravalli, J., Madayiputhiya, N., Adamec, J., Case, A. J., & Zimmerman, M. C.
(2015).
Rapid metabolism of exogenous angiotensin II by catecholaminergic neuronal cells in culture media. Physiological Reports.
3(2), e12287-e12287.
-
Moore, T. A., Ahmad, I., Jones, J., Case, A., & Zimmerman, M.
(2014).
101 Superoxide and Superoxide Dismutase Levels in High-Risk Pregnant Women: A Pilot Feasibility Study. Free Radical Biology and Medicine.
76, s51-S51.
-
Basu, U., Case, A. J., Liu, J., Li, Y., & Zimmerman, M. C.
(2014).
72 Overexpression of Redox-Sensitive Calcium/calmodulin-Dependent Protein Kinase II (CaMKII) in Central Neurons Augments Angiotensin II (AngII)-Induced Hypertension. Free Radical Biology and Medicine.
76, s41-S41.
-
Case, A. J., & Zimmerman, M. C.
(2014).
76 Redox-Regulated Suppression of Resting Splenic TLymphocytes during Sympathoexcitation-Associated Hypertension. Free Radical Biology and Medicine.
76, s42-s43.
-
BASU, U., Case, A. J., Liu, J., Li, Y., & Zimmerman, M. C.
(2014).
Abstract 201: Overexpression of Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Potentiates Angiotensin II (AngII)-Mediated Signaling in Neurons. HYPERTENSION.
64(suppl_1),
-
Case, A. J., & Zimmerman, M. C.
(2014).
Abstract 253: Norepinephrine Suppresses T-lymphocyte Growth and Cytokine Production via Superoxide During Hypertension. HYPERTENSION.
64(suppl_1),
-
Case, A. J., & Domann, F. E.
(2014).
Absence of manganese superoxide dismutase delays p53-induced tumor formation. Redox Biology.
2, 220-223.
-
Case, A. J., O'Leary, B. R., Stipp, C. S., Domann, F. E., & Mezhir, J. J.
(2013).
4 Catalytically Inactive Extracellular Superoxide Dismutase Reduces Pancreatic Tumor Cell Invasion. Free Radical Biology and Medicine.
65, s16-S16.
-
Sobhakumari, A., Schickling, B. M., Love-Homan, L., Raeburn, A., Fletcher, E., Case, A. J., ... Simons, A. L.
(2013).
NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells. TOXICOLOGY AND APPLIED PHARMACOLOGY.
272(3), 736-745.
-
Case, A. J., Liu, M., Ding, S., & Zimmerman, M. C.
(2013).
PSS134 Nitration of the Tyrosine in Angiotensin II Attenuates its Biological Activity. Free Radical Biology and Medicine.
65, s69-S69.
-
Basu, U., Case, A. J., Madayiputhiya, N., & Zimmerman, M. C.
(2013).
Abstract 152: Development of a Chronic Angiotensin II (AngII)-stimulated Neuronal Cell Culture Model. HYPERTENSION.
62(suppl_1),
-
Case, A. J., Li, S., Basu, U., Tian, J., & Zimmerman, M. C.
(2013).
Mitochondrial-localized NADPH oxidase 4 is a source of superoxide in angiotensin II-stimulated neurons. American Journal of Physiology. Heart and Circulatory Physiology.
305(1), H19-H28.
-
Case, A. J., Cruz, R. F., & Zimmerman, M. C.
(2013).
Hydrogen peroxide (H2O2) is not increased in angiotensin II (AngII)stimulated neurons overexpressing superoxide dismutase (SOD). The FASEB Journal.
27(S1), 1143.15-1143.15.
-
Case, A. J., Madsen, J. M., Motto, D. G., Meyerholz, D. K., & Domann, F. E.
(2013).
Manganese superoxide dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis, globin switching, and epigenetic control in erythrocyte precursor cells. Free Radical Biology and Medicine.
56, 17-27.
-
Cyr, A. R., Brown, K. E., McCormick, M. L., Coleman, M. C., Case, A. J., Watts, G. S., ... Domann, F. E.
(2013).
Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes. 1(1), 172-177.
-
Li, S., Case, A. J., Yang, R., Schultz, H. D., & Zimmerman, M. C.
(2013).
Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide. 2, 8-14.
-
Case, A. J., Madsen, J. M., Motto, D. G., Meyerholz, D. K., & Domann, F. E.
(2012).
Disruption of Mitochondrial Superoxide Flux Causes Abnormal Heme Synthesis and Hemoglobin Gene Regulation in Erythroid Precursor Cells. Free Radical Biology and Medicine.
53, s17-S17.
-
Case, A. J., & Domann, F. E.
(2012).
Manganese superoxide dismutase is dispensable for post-natal development and lactation in the murine mammary gland. FREE RADICAL RESEARCH.
46(11), 1361-1368.
-
Case, A. J., Mezhir, J. J., O'Leary, B. R., Hrabe, J. E., & Domann, F. E.
(2012).
Rational design of a secreted enzymatically inactive mutant of extracellular superoxide dismutase. 17(6), 239-245.
-
Hrabe, J. E., Case, A. J., O'Leary, B. R., Place, T. L., Olivier, A. K., Henry, M. D., Domann, F. E., & Mezhir, J. J.
(2012).
Extracellular superoxide dismutase promotes pancreatic cancer liver metastasis. Journal of the American College of Surgeons.
215(3), s131-S131.
-
Fletcher, E., Sobhakumari, A., Brown, C. O., Case, A. J., Spitz, D. R., Domann, F. E., Goel, A., & Simons, A. L.
(2011).
EGFR Inhibition Induces IL6 Expression Via NOX4 in Head and Neck Cancer Cells. Free Radical Biology and Medicine.
51, s133-s134.
-
Mao, G., Jacobus, J., Martin, S., Case, A., Aykin-Burns, N., Mapuskar, K., ... Spitz, D. R.
(2011).
Sirtuin 3/Thymocytes Demonstrate Increased Levels of Superoxide, a Diminished Radiation-Induced Adaptive Response, and Accelerated Bax-Induced Thymic Lymphoma in the C57BL/6 mice. Free Radical Biology and Medicine.
51, s125-s126.
-
Case, A. J., McGill, J. L., Tygrett, L. T., Shirasawa, T., Spitz, D. R., Waldschmidt, T. J., Legge, K. L., & Domann, F. E.
(2011).
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge. Free Radical Biology and Medicine.
50(3), 448-458.
-
Place, T. L., Fitzgerald, M. P., Venkataraman, S., Vorrink, S. U., Case, A. J., Teoh, M., & Domann, F. E.
(2011).
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PLoS ONE.
6(1), e14617-e14617.
-
Fitzgerald, M. P., Gourronc, F., Teoh, M., Provenzano, M. J., Case, A. J., Martin, J. A., & Domann, F. E.
(2011).
Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis. Sarcoma.
2011, 598218-11.
-
Case, A. J., & Domann, F. E.
(2010).
Epigenetic Control of Prolyl and Asparaginyl Hydroxylases in Prostate Cancer
-
Case, A. J., & Domann, F. E.
(2010).
A Novel Role for Mitochondrial Superoxide in the Development of Erythropoietic Protoporphyria. Free Radical Biology and Medicine.
49, s92-S92.
-
Cyr, A. R., Case, A. J., Mao, G., & Domann, F. E.
(2010).
Conditional Knockout of Sod2 in Murine Hepatocytes Disrupts Epigenetic Control of Gene Expression. Free Radical Biology and Medicine.
49, s128-S128.
-
Mao, G., Jacobus, J. A., Martin, S. M., Case, A. J., Aykin-Burns, N., Mapuskar, K., ... Spitz, D. R.
(2010).
Low Dose (10-100cGy) Whole Body Irradiation Increases Steady-state Levels of Superoxide in C57BL/6 Thymocytes. Free Radical Biology and Medicine.
49, s66-S66.
-
Case, A. J., Wagner, B. A., Buettner, G. R., & Domann, F. E.
(2009).
Deficiency of MnSOD in Hematopoietic Stem Cells Causes a Sideroblastic Anemia-Like Phenotype. Blood.
114(22), 1991-1991.
-
Case, A. J., Mcgill, J. L., Sangster, S. C., Madsen, J. M., Tygrett, L. T., Johns, A. G., ... Domann, F. E.
(2009).
Heightened Susceptibility to Influenza Mortality in Immunodeficient Mice Caused by a T-Cell Specific Defect in SOD2. Blood.
114(22), 1655-1655.
-
Nam, C., Case, A. J., Hostager, B. S., & O'Dorisio, M. S.
(2009).
The role of vasoactive intestinal peptide (VIP) in megakaryocyte proliferation. Journal of Molecular Neuroscience.
37(2), 160-167.
-
Lauten, T. H., Elkhatib, S. K., Natour, T., Reed, E. C., Jojo, C. N., & Case, A. J.
(2024).
Beta-adrenergic signaling and T-lymphocyte-produced catecholamines are necessary for interleukin 17A synthesis. 2024.06.05.597633.
-
chapter
-
Case, A. J., & Domann, F. E.
(2009).
HypoxiaInduced Gene Regulation through Hypoxia Inducible Factor1. Redox Signaling and Regulation in Biology and Medicine.
(pp. 207-227).
Wiley.
-
Case, A. J., & Domann, F. E.
(2009).
HypoxiaInduced Gene Regulation through Hypoxia Inducible Factor1. Redox Signaling and Regulation in Biology and Medicine.
(pp. 207-227).
Wiley.
-
conference paper
-
Reed, E., Lauten, T., Clopp, A., Moshfegh, C., Elkhatib, S., & Case, A.
(2022).
Mitochondrial Regulation of Inflammation after Psychological Trauma. Free Radical Biology and Medicine.
34-34.
-
Moshfegh, C., Elkhatib, S., Watson, G., & Case, A.
(2022).
Calprotectin is Protective during Psychological Trauma. Free Radical Biology and Medicine.
85-85.
-
Elkhatib, S., Moshfegh, C., Watson, G., & Case, A.
(2022).
T-Lymphocyte Tyrosine Hydroxylase Regulates IL-17A Downstream of Mitochondrial Superoxide. Free Radical Biology and Medicine.
81-82.
-
Reed, E., Lauten, T., Clopp, A., Moshfegh, C., Elkhatib, S., & Case, A.
(2022).
Mitochondrial Regulation of Inflammation after Psychological Trauma. Free Radical Biology and Medicine.
34-34.
-
institutional repository document
-
Moshfegh, C. M., Elkhatib, S. K., Watson, G. F., Drake, J., Taylor, Z. N., Reed, E. C., ... Case, A. J.
(2022).
S100a9 Attenuates Inflammation during Repeated Social Defeat Stress
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2022).
T-lymphocyte Tyrosine Hydroxylase Regulates TH17 T-lymphocytes during Repeated Social Defeat Stress
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., Schwab, A. D., Katsurada, K., Patel, K. P., & Case, A. J.
(2021).
Splenic denervation attenuates repeated social defeat stress-induced T-lymphocyte inflammation
-
Elkhatib, S. K., Moshfegh, C. M., Watson, G. F., & Case, A. J.
(2020).
Inflammation is a stronger predictor of psychological trauma exposure than behavior in repeated social defeat
-
Reed, E. C., Silva, V. A., Giebel, K. R., Natour, T., Lauten, T. H., Jojo, C. N., Schleiker, A. E., & Case, A. J.
Hemoglobin alpha is a redox-sensitive mitochondrial-related protein in T-lymphocytes
-
Moshfegh, C. M., Elkhatib, S. K., Watson, G. F., Drake, J., Taylor, Z. N., Reed, E. C., ... Case, A. J.
(2022).
S100a9 Attenuates Inflammation during Repeated Social Defeat Stress
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- BIMS491 Hnr-research Instructor
- GENE491 Hnr-research Instructor
- GENE691 Research Instructor
- GENE691 Research Instructor
- MPHY685 Directed Studies Instructor
- MSCI685 Directed Studies Instructor
- MSCI689 Sptp: Foundat Psychiatric Rese Instructor
- MSCI691 Research Credit: Medical Sci Instructor
- NRSC491 Hnr-research Instructor
Background
education and training
- Ph.D. in Free Radical and Radiation Biology, University of Iowa - (Iowa City, Iowa, United States) 2011
- B.S. in Biochemistry, University of Iowa - (Iowa City, Iowa, United States) 2004
- University of Nebraska Medical Center - (Omaha, Nebraska, United States) , Postdoctoral Training 2015
- University of Iowa Hospitals and Clinics - (Iowa City, Iowa, United States) , Postdoctoral Training 2012
Contact
first name
- Adam
has last name
- Case
mailing address
-
8447 Riverside Pkwy
3414 MREB2
C/O Adam Case
Bryan, TX 77807
USA
Other
- acase@tamu.edu