Association of chest compression pause duration prior to E-CPR cannulation with cardiac arrest survival outcomes. Academic Article uri icon


  • OBJECTIVE: To characterize chest compression (CC) pause duration during the last 5 minutes of pediatric cardiopulmonary resuscitation (CPR) prior to extracorporeal-CPR (E-CPR) cannulation and the association with survival outcomes. METHODS: Cohort study from a resuscitation quality collaborative including pediatric E-CPR cardiac arrest events10min with CPR quality data. We characterized CC interruptions during the last 5min of defibrillator-electrode recorded CPR (prior to cannulation) and assessed the association between the longest CC pause duration and survival outcomes using multivariable logistic regression. RESULTS: Of 49 E-CPR events, median age was 2.0 [Q1, Q3: 0.6, 6.6] years, 55% (27/49) survived to hospital discharge and 18/49 (37%) with favorable neurological outcome. Median duration of CPR was 51 [43, 69] min. During the last 5min of recorded CPR prior to cannulation, median duration of the longest CC pause was 14.0 [6.3, 29.4] sec: 66% >10 sec, 25% >29 sec, 14% >60 sec, and longest pause 168 sec. Following planned adjustment for known confounders of age and CPR duration, each 5-sec increase in longest CC pause duration was associated with lower odds of survival to hospital discharge [adjusted OR 0.89, 95%CI: 0.79-0.99] and lower odds of survival with favorable neurological outcome [adjusted OR 0.77, 95%CI: 0.60-0.98]. CONCLUSIONS: Long CC pauses were common during the last 5min of recorded CPR prior to E-CPR cannulation. Following adjustment for age and CPR duration, each 5-second incremental increase in longest CC pause duration was associated with significantly decreased rates of survival and favorable neurological outcome.

published proceedings

  • Resuscitation

altmetric score

  • 18.33

author list (cited authors)

  • Lauridsen, K. G., Lasa, J. J., Raymond, T. T., Yu, P., Niles, D., Sutton, R. M., ... pediRES-Q Investigators.

citation count

  • 2

complete list of authors

  • Lauridsen, Kasper G||Lasa, Javier J||Raymond, Tia T||Yu, Priscilla||Niles, Dana||Sutton, Robert M||Morgan, Ryan W||Fran Hazinski, Mary||Griffis, Heather||Hanna, Richard||Zhang, Xuemei||Berg, Robert A||Nadkarni, Vinay M

publication date

  • August 2022