Hemodynamic-directed cardiopulmonary resuscitation during in-hospital cardiac arrest.
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Cardiopulmonary resuscitation (CPR) guidelines assume that cardiac arrest victims can be treated with a uniform chest compression (CC) depth and a standardized interval administration of vasopressor drugs. This non-personalized approach does not incorporate a patient's individualized response into ongoing resuscitative efforts. In previously reported porcine models of hypoxic and normoxic ventricular fibrillation (VF), a hemodynamic-directed resuscitation improved short-term survival compared to current practice guidelines. Skilled in-hospital rescuers should be trained to tailor resuscitation efforts to the individual patient's physiology. Such a strategy would be a major paradigm shift in the treatment of in-hospital cardiac arrest victims.
author list (cited authors)
Sutton, R. M., Friess, S. H., Maltese, M. R., Naim, M. Y., Bratinov, G., Weiland, T. R., ... Berg, R. A.
complete list of authors
Sutton, Robert M||Friess, Stuart H||Maltese, Matthew R||Naim, Maryam Y||Bratinov, George||Weiland, Theodore R||Garuccio, Mia||Bhalala, Utpal||Nadkarni, Vinay M||Becker, Lance B||Berg, Robert A