Hemodynamic-directed cardiopulmonary resuscitation during in-hospital cardiac arrest. Academic Article uri icon


  • Cardiopulmonary resuscitation (CPR) guidelines assume that cardiac arrest victims can be treated with a uniform chest compression (CC) depth and a standardized interval administration of vasopressor drugs. This non-personalized approach does not incorporate a patient's individualized response into ongoing resuscitative efforts. In previously reported porcine models of hypoxic and normoxic ventricular fibrillation (VF), a hemodynamic-directed resuscitation improved short-term survival compared to current practice guidelines. Skilled in-hospital rescuers should be trained to tailor resuscitation efforts to the individual patient's physiology. Such a strategy would be a major paradigm shift in the treatment of in-hospital cardiac arrest victims.

published proceedings

  • Resuscitation

altmetric score

  • 73.06

author list (cited authors)

  • Sutton, R. M., Friess, S. H., Maltese, M. R., Naim, M. Y., Bratinov, G., Weiland, T. R., ... Berg, R. A.

citation count

  • 60

complete list of authors

  • Sutton, Robert M||Friess, Stuart H||Maltese, Matthew R||Naim, Maryam Y||Bratinov, George||Weiland, Theodore R||Garuccio, Mia||Bhalala, Utpal||Nadkarni, Vinay M||Becker, Lance B||Berg, Robert A

publication date

  • August 2014