Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy. Academic Article

abstract

• Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death. We describe 2 dogs with severe, symptomatic Chagas cardiomyopathy characterized by myocardial dysfunction and electrocardiographic abnormalities that were managed with a combination of cardiac medications and antiparasitic treatment with itraconazole and amiodarone. Both dogs died suddenly within 6months of diagnosis. These cases highlight the need for early detection of Chagas disease in dogs and continued research to develop effective antiparasitic treatment protocols.

authors

• Hamer, Sarah
• Saunders, Ashley

published proceedings

• J Vet Intern Med

altmetric score

• 0.5

author list (cited authors)

• Malcolm, E. L., Saunders, A. B., Vitt, J. P., Boutet, B. G., & Hamer, S. A.

citation count

• 5

publication date

• May 2022

publisher

• Wiley  Publisher

keywords

• Amiodarone
• Animals
• Anti-Infective Agents
• Antiparasitic Agents
• Arrhythmias, Cardiac
• Canine
• Chagas Cardiomyopathy
• Dog Diseases
• Dogs
• Itraconazole
• Myocarditis
• Treatment
• Trypanosoma Cruzi
• Ventricular Tachycardia

Digital Object Identifier (DOI)

• 10.1111/jvim.16422

start page

• 1100

end page

• 1105

volume

• 36

issue

• 3

URL

• http://dx.doi.org/10.1111/jvim.16422

user-defined tag

• 3 Good Health and Well-Being