Clostridioides difficile spore germination: initiation to DPA release.

abstract

• Germination by Clostridioides difficile spores is an essential step in pathogenesis. Spores are metabolically dormant forms of bacteria that resist severe conditions. Work over the last 10 years has elucidated that C. difficile spores germinate thorough a novel pathway. This review summarizes our understanding of C. difficile spore germination and the factors involved in germinant recognition, cortex degradation and DPA release.

authors

• Sorg, Joseph

published proceedings

• Curr Opin Microbiol

altmetric score

• 0.25

author list (cited authors)

• Baloh, M., & Sorg, J. A.

citation count

• 1

complete list of authors

• Baloh, Marko||Sorg, Joseph A

publication date

• January 2022

publisher

• Elsevier  Publisher

published in

• Current Opinion in Microbiology  Journal

keywords

• Bacterial Proteins
• Clostridioides
• Clostridioides Difficile
• Spores, Bacterial

Digital Object Identifier (DOI)

• 10.1016/j.mib.2021.11.001

start page

• 101

end page

• 107

volume

• 65

URL

• http://dx.doi.org/10.1016/j.mib.2021.11.001