The Probability of Fusions Joining Sex Chromosomes and Autosomes Institutional Repository Document uri icon


  • AbstractChromosome fusion and fission are primary mechanisms of karyotype evolution. In particular, the fusion of a sex chromosome and an autosome has been proposed as a mechanism to resolve intralocus sexual antagonism. If sexual antagonism is common throughout the genome, we should expect to see an excess of fusions that join sex chromosomes and autosomes. Here, we present a null model that provides the probability of a sex chromosome autosome fusion, assuming all chromosomes have an equal probability of being involved in a fusion. This closed-form expression is applicable to both male and female heterogametic sex chromosome systems and can accommodate unequal proportions of fusions originating in males and females.

altmetric score

  • 7.15

author list (cited authors)

  • Anderson, N. W., & Blackmon, H.

citation count

  • 1

complete list of authors

  • Anderson, Nathan W||Blackmon, Heath

Book Title

  • bioRxiv

publication date

  • March 2020