The diafiltration method for the study of the binding of macromolecules to heavy metals Academic Article uri icon


  • A membrane process known as continuous diafiltration has been utilized as an effective method for the study of the binding of macromolecules to ions. Data from one experiment will result in an entire isotherm when temperature and pH are closely controlled. This paper discusses the theory of continuous diafiltration and describes a procedure for quantifying variable membrane rejection behavior. The binding of five heavy metals (Cd, Cu, Ni, Pb, Zn) individually and collectively, to natural lecithin was studied. Copper exhibited stronger binding when it was the lone ion compared to when it was in a mixture of the five metals. Further, the membrane rejected copper at a constant rate of 10% in the first case compared to a variable rate with an average of 79% in the second. This work was performed to characterization the binding of lecithin to heavy metals as a step in the development of a treatment technique termed micellar enhanced ultrafiltration. © 1994.

author list (cited authors)

  • Ahmadi, S., Batchelor, B., & Koseoglu, S. S.

citation count

  • 27

publication date

  • April 1994