Hypercoagulation from Concomitant Administration of Tamoxifen and Warfarin. Academic Article uri icon

abstract

  • Tamoxifencausing an increase in the anticoagulation effect of warfarin is suggested to be clinically significant, but cases so far have been largely undocumented. Current recommendations adviseclinicians to proceed with caution during concomitant therapy. In the presence of other medications known to interact with warfarin, such as antibiotics, proton pump inhibitors, amiodarone, and azole antifungals, international normalized ratio (INR) elevations can possibly be exacerbated even further. We hereby present a case report and a review of significant literature on the use of tamoxifen and warfarin concurrently.

published proceedings

  • Cureus

author list (cited authors)

  • Panahi, L., Saenz Ii, J. A., Nguyen, N., Udeani, G., & Surani, S.

citation count

  • 2

complete list of authors

  • Panahi, Ladan||Saenz Ii, Javier A||Nguyen, Nam||Udeani, George||Surani, Salim

publication date

  • May 2020

publisher

published in