Hepatotoxicity Secondary to Levofloxacin Use. Academic Article uri icon

abstract

  • Levofloxacin is a broad-spectrum antibiotic that is used in the treatment of many infections.A rare adverse drug reaction following the use of levofloxacin is drug-induced liver injury.The exact mechanism behindfluoroquinolone-inducedliverinjury is unknown,but many severe, sometimes fatalhepatotoxicity cases are reported.Current recommendations advise clinicians to discontinuelevofloxacin immediatelyif the patient develops signs and symptoms of hepatitis.This case report presents a 79-year-oldmale who was prescribed levofloxacin 500mg by mouth daily for seven days. The patient had a past medical history of dementia, seizures, cerebral vascular accident, pulmonary fibrosis, and chronic kidney disease.Uponadmission,the patient began to show signs and symptoms of liver injury.We hereby present a case report and a review of significant literature onlevofloxacin-induced liver injury.

published proceedings

  • Cureus

author list (cited authors)

  • Panahi, L., Surani, S. S., Udeani, G., Patel, N. P., & Sellers, J.

citation count

  • 1

complete list of authors

  • Panahi, Ladan||Surani, Salim Surani||Udeani, George||Patel, Niraj P||Sellers, Jacob

publication date

  • June 2021

publisher

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