Ab initio study of the lowest energy conformers and IR spectra of poly(amidoamine)-G0 dendrimers Academic Article uri icon


  • A systematic sequential procedure is implemented to find local minimum conformers corresponding to the lowest generation (G0), -NH 2- and -OH-tenninated, poly(amidoamine) (PAMAM) dendrimers, and their IR vibrational spectra using ab initio (Hartree-Fock and density functional theory) techniques. It is found that the most stable conformations of PAMAM-G0 dendrimers in the gas phase have all their secondary amide groups in the trans conformation. Interbranch interactions including intramolecular H-bonds play a definite role in providing structural stability. The calculated electronic density spatial distribution reveals the existence of three regions where appropriate environments would attract either an ion or a metal atom: the core, the amide, and the terminal group (NH 2 or OH) sites. A detailed analysis of the IR spectra for the lowest energy conformers of PAMAMPolym-NH 2: and PAMAM-OH is thoroughly analyzed and compared with experimental data when available.

published proceedings


author list (cited authors)

  • Tarazona-Vasquez, F., & Balbuena, P. B.

citation count

  • 36

complete list of authors

  • Tarazona-Vasquez, F||Balbuena, PB

publication date

  • October 2004