Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?

abstract

• In a cohort of 480 patients admitted to an acute care hospital, 68 (14%) had positive perirectal cultures for toxigenic Clostridioides difficile on admission. Of the 11 patients (2%) diagnosed with healthcare-associated C. difficile infections, 3 (27%) had genetically related admission and infection isolates, based on whole-genome sequencing.

authors

• Jinadatha, Chetan

published proceedings

• Clin Infect Dis

altmetric score

• 20.45

author list (cited authors)

• Gonzalez-Orta, M., Saldana, C., Ng-Wong, Y., Cadnum, J., Jencson, A., Jinadatha, C., & Donskey, C. J.

citation count

• 7

publication date

• January 2019

publisher

• Oxford University Press (OUP)  Publisher

published in

• Clinical Infectious Diseases  Journal

keywords

• Adult
• Aged
• Aged, 80 And Over
• Carrier State
• Clostridioides Difficile
• Clostridium Infections
• Colonization
• Cross Infection
• Female
• Genome, Bacterial
• Healthcare-associated
• Hospitalization
• Humans
• Infection Control
• Male
• Middle Aged
• Patient Admission
• Prospective Studies
• Rectum
• Risk Factors
• Whole Genome Sequencing
• Young Adult

PubMed Central ID

• 30855075

Digital Object Identifier (DOI)

• 10.1093/cid/ciz189

start page

• 1801

end page

• 1804

volume

• 69

issue

• 10

URL

• http://dx.doi.org/10.1093/cid/ciz189

user-defined tag

• 3 Good Health and Well-Being