Nasopharyngeal bacterial and fungal microbiota in normal horses and horses with nasopharyngeal cicatrix syndrome Academic Article uri icon

abstract

  • Background

    The nasopharyngeal bacterial and fungal microbiota of normal horses and those with nasopharyngeal cicatrix syndrome (NCS) are unknown.

    Hypotheses/objectives

    To describe the microbiota from nasopharyngeal washes of healthy horses and of horses acutely affected with NCS.

    Animals

    Twenty-six horses acutely affected with NCS horses and 14 unaffected horses.

    Methods

    Prospective, observational cohort study. Horses were recruited by investigators through personal communications in central Texas. Bacterial (16s RNA) and fungal (internal transcribed spacer) microbiota from nasopharyngeal washes were evaluated. Polymerase chain reaction for detection of Pythium insidiosum was performed.

    Results

    Results indicated that 6 fungal genera (Alternaria, Bipolaris, Microascus, Spegazzinia, Paraconiothyrium, Claviceps) and 1 bacterial genera (Staphylococcus) were significantly different between affected and unaffected horses. The fungal genus Bipolaris had increased abundance in NCS affected horses and on NCS affected farms. Pythium insidiosum was absent in the nasopharyngeal wash of all horses, irrespective of health status.

    Conclusion and clinical importance

    Significant differences were identified in the fungal microbiota in horses affected with NCS and farms affected with NCS compared to those unaffected. Therefore, Bipolaris warrants further investigation.

published proceedings

  • Journal of Veterinary Internal Medicine

altmetric score

  • 0.25

author list (cited authors)

  • Rodríguez, N., Whitfield‐Cargile, C. M., Chamoun‐Emanuelli, A. M., Hildreth, E., Jordan, W., & Coleman, M. C.

citation count

  • 0

complete list of authors

  • Rodríguez, Natalia||Whitfield‐Cargile, Canaan M||Chamoun‐Emanuelli, Ana M||Hildreth, Elizabeth||Jordan, Will||Coleman, Michelle C

publication date

  • November 2021

publisher