Compositions and methods for drug sensitization of parasites Patent uri icon

abstract

  • Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a an arylphenoxypropionate derivative, an aryloxyphenoxyacetate derivative, an aryloxyphenylacetate derivative, one or more substituted quinols, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof, or a combination thereof in an amount and formulation sufficient to sensitize the parasite to the drug, treating infection of a patient by a parasite with a drug, or to prevent symptomatic infection of a patient by a parasite with a drug.

author list (cited authors)

  • Reddy, M., Sacchettini, J. C., Zhou, N. E., & McCutchen, B. F.

complete list of authors

  • Reddy, Manchi CM||Sacchettini, James C||Zhou, Nian E||McCutchen, Billy F