More than an on-and-off switch: Post-translational modifications of plant pattern recognition receptor complexes. Academic Article

abstract

• Sensing microbe-associated molecular patterns (MAMPs) by cell surface-resident pattern recognition receptors (PRRs) constitutes a core process in launching a successful immune response. Over the last decade, remarkable progress has been made in delineating the mechanisms of PRR-mediated plant immunity. As the frontline of defense, the homeostasis, activities, and subcellular dynamics of PRR and associated regulators are subjected to tight regulations. The layered protein post-translational modifications, particularly the intertwined phosphorylation and ubiquitylation of PRR complexes, play a central role in regulating PRR signaling outputs and plant immune responses. This review provides an update about the PRR complex regulation by various post-translational modifications and discusses how protein phosphorylation and ubiquitylation act in concert to ensure a rapid, proper, and robust immune response.

authors

• He, Ping
• Shan, Libo

published proceedings

• Curr Opin Plant Biol

author list (cited authors)

• Kong, L., Rodrigues, B., Kim, J. H., He, P., & Shan, L.

citation count

• 12

complete list of authors

• Kong, Liang||Rodrigues, Barbara||Kim, Jun Hyeok||He, Ping||Shan, Libo

publication date

• January 2021

publisher

• Elsevier  Publisher

published in

• Current Opinion in Plant Biology  Journal

keywords

• Mamps
• Phosphorylation
• Plant Immunity
• Plants
• Post-translational Modifications
• Protein Processing, Post-Translational
• Prr Complex
• Receptors, Pattern Recognition
• Signal Transduction
• Ubiquitylation

Digital Object Identifier (DOI)

• 10.1016/j.pbi.2021.102051

start page

• 102051

end page

• 102051

volume

• 63

URL

• http://dx.doi.org/10.1016/j.pbi.2021.102051