Evaluation of a Mobile Phone-Based Microscope for Screening of Schistosoma haematobium Infection in Rural Ghana Academic Article uri icon

abstract

  • AbstractSchistosomiasis affects over 170 million people in Africa. Here we compare a novel, low-cost mobile phone microscope to a conventional light microscope for the label-free diagnosis of Schistosoma haematobium infections in a rural Ghanaian school setting. We tested the performance of our handheld microscope using 60 slides that were randomly chosen from an ongoing epidemiologic study in school-aged children. The mobile phone microscope had a sensitivity of 72.1% (95% confidence interval [CI]: 56.1-84.2), specificity of 100% (95% CI: 75.9-100), positive predictive value of 100% (95% CI: 86.3-100), and a negative predictive value of 57.1% (95% CI: 37.4-75.0). With its modest sensitivity and high specificity, this handheld and cost-effective mobile phone-based microscope is a stepping-stone toward developing a powerful tool in clinical and public health settings where there is limited access to conventional laboratory diagnostic support.

published proceedings

  • The American Journal of Tropical Medicine and Hygiene

altmetric score

  • 16.45

author list (cited authors)

  • Bogoch, I. I., Koydemir, H. C., Tseng, D., Ephraim, R., Duah, E., Tee, J., Andrews, J. R., & Ozcan, A.

citation count

  • 27

complete list of authors

  • Bogoch, Isaac I||Koydemir, Hatice C||Tseng, Derek||Ephraim, Richard KD||Duah, Evans||Tee, Joseph||Andrews, Jason R||Ozcan, Aydogan

publication date

  • June 2017