Maternal obesity alters the expression of embryonic regulatory transcripts in the preimplantation ovine conceptus. Academic Article

abstract

• The influence of exposure to overfeeding-induced maternal obesity around the time of conception on early embryogenesis was examined in the day 14 ovine conceptus. The relative abundance of FGFR2 and DNMT1 was influenced by maternal obesity status and conceptus sex, and the abundance of PPARG and PTGS2 transcripts was greater in male conceptuses regardless of the obesity status of the ewe. These observations demonstrated that short-term exposure to maternal obesity impacts early conceptus transcript patterning.

authors

• Poole, Rebecca

published proceedings

• Reprod Biol

altmetric score

• 0.25

author list (cited authors)

• McCoski, S. R., Poole, R. K., Vailes, M. T., & Ealy, A. D.

citation count

• 1

complete list of authors

• McCoski, Sarah R||Poole, Rebecca K||Vailes, McCauley T||Ealy, Alan D

publication date

• January 2018

publisher

• Elsevier  Publisher

published in

• REPRODUCTIVE BIOLOGY  Journal

keywords

• Animals
• Blastocyst
• Cyclooxygenase 2
• Dna (cytosine-5-)-methyltransferase 1
• EMBRYO
• Embryo Implantation
• Female
• Maternal Nutritional Physiological Phenomena
• PPAR Gamma
• Placenta
• Pregnancy
• Receptor, Fibroblast Growth Factor, Type 2
• Sheep
• Sheep, Domestic

Digital Object Identifier (DOI)

• 10.1016/j.repbio.2018.05.001

start page

• 198

end page

• 201

volume

• 18

issue

• 2

URL

• http://dx.doi.org/10.1016/j.repbio.2018.05.001