Zinc thiotropolone combinations as inhibitors of the SARS-CoV-2 main protease Academic Article uri icon

abstract

  • Inorganic synthesis and characterization of zinc thiotropolone complexes, computational docking studies and the influence of ligand/zinc concentrations on protease enzyme inhibition indicate a “Goldilock's” effect for most effective combinations.

published proceedings

  • Dalton Transactions

altmetric score

  • 0.25

author list (cited authors)

  • DeLaney, C., Sheng, Y., Pectol, D. C., Vantansever, E., Zhang, H., Bhuvanesh, N., ... Darensbourg, M. Y.

citation count

  • 2

complete list of authors

  • DeLaney, Christopher||Sheng, Yan||Pectol, D Chase||Vantansever, Erol||Zhang, Hanyuan||Bhuvanesh, Nattamai||Salas, Isaiah||Liu, Wenshe R||Fierke, Carol F||Darensbourg, Marcetta Y

publication date

  • September 2021