Neural circuits driving larval locomotion in Drosophila. Academic Article

abstract

• More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed fundamental insights into our understanding of axon guidance mechanisms, neural differentiation, and early cell fate decisions. What is less understood is how a group of neurons from disparate anterior-posterior axial positions, lineages and developmental periods of neurogenesis coalesce to form a functional circuit. Using neurogenetic techniques developed in Drosophila it is now possible to study the neural substrates of behavior at single cell resolution. New mapping tools described in this review, allow researchers to chart neural connectivity to better understand how an anatomically simple organism performs complex behaviors.

authors

• Arzan Zarin, Aref

published proceedings

• Neural Dev

altmetric score

• 171.75

author list (cited authors)

• Clark, M. Q., Zarin, A. A., Carreira-Rosario, A., & Doe, C. Q.

citation count

• 55

complete list of authors

• Clark, Matthew Q||Zarin, Aref Arzan||Carreira-Rosario, Arnaldo||Doe, Chris Q

publication date

• April 2018

publisher

• Springer Nature  Publisher

published in

• Neural Development  Journal

keywords

• Animals
• Drosophila
• Larva
• Locomotion
• Locomotor Circuits
• Multisensory Integration
• Navigation
• Nerve Net
• Neurodevelopment
• Sensorimotor
• Wave Propagation

PubMed Central ID

• 29673388

Digital Object Identifier (DOI)

• 10.1186/s13064-018-0103-z

start page

• 6

volume

• 13

issue

• 1

URL

• http://dx.doi.org/10.1186/s13064-018-0103-z